Conserved Protein Domain Family
DUF4541

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pfam15074: DUF4541 
Domain of unknown function (DUF4541)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 100 and 163 amino acids in length. There is a conserved KLHRDDR sequence motif. There is a single completely conserved residue Y that may be functionally important. In humans, the gene is found in the chromosomal location, C5orf49.
Statistics
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PSSM-Id: 405720
View PSSM: pfam15074
Aligned: 22 rows
Threshold Bit Score: 95.3962
Threshold Setting Gi: 514685849
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFN69319     182 TYFDNRKREGrIAdvgSAYDRLHDVTP----FDPSKPRCDRTKpsLIWAEIHEENKRHAVPMTANHWYSRpnRIQIDYPD 257 Florida carpent...
XP_004990503  30 GFFGSPNKLAtKTlseTMYDRQMHVPEq--dKSSKLHRDDRQS--RVGLDIHKEERERAFPVRSSSLYGA--RAPIDNLV 103 Salpingoeca ros...
XP_001637985  83 SYFNNGKQQT-RV---LTYDRMFKIKQg---YCSKLHRDDRQH--TDAFDVHAEECEKAVPVLTSSQYGR--RPPLETPQ 151 starlet sea ane...
XP_003385783  59 SYFDNQKTHK-RD---YDYDMTFCVNEg---YNQKLKRDDMQH--TQGLNIRGEEENKPVPILSNSVYGK--GAPLESMT 127 Amphimedon quee...
EFA05823      43 TYFDNPMKRQhRS---AEYDLFFAYTKvfplWDPRKPKDNCQYlrDIRENIYQQEKAKPVPVLTSLNYGLaaRRLLDQPE 119 red flour beetle
XP_002612505  56 TVYNNNKEHQ-EK---SAYERLFNQESd---YNSKLHRDDRQH--TVGLNVHAEETSKAVPLRSSSQYGFllNRPCDPPM 126 Florida lancelet
Q9DAR0        77 SYFSREGQTG-IV---SLYDCVFKRRLd---YNQKLHRDDREHakNLGLHINEEEQERTVPVLMSSVYGKriNQPIEPLN 149 house mouse
A4QMS7        42 SYYYRPARTG-II---SLYDCIFKRRLd---YDQKLHRDDREHakSLGLHVNEEEQERPVGVLTSSVYGKriNQPIEPLN 114 human
XP_003443825  32 SYFNNEPKVS-DV---SMYDRLNNHVEg---YDMRLPRDDRKHwkGRGLDINKEERSRTVPVLSSSEYGRrpAPALYVPE 104 Nile tilapia
XP_002665577  32 RYFNCSIKAP-ER---SLYDCLHQSIEg---FDNKLHRDDRKHakARGLDIFSEESSRPAPVLCSSVYGRf-SPLHYDSS 103 zebrafish
EFN69319     258 M-RFARSSKTR-DFYSRN 273 Florida carpenter ant
XP_004990503 104 HmANGRKKVVSqEFYSKE 121 Salpingoeca rosetta
XP_001637985 152 R-KHVRVATVKrDFYRYS 168 starlet sea anemone
XP_003385783 128 R-DYVRVAVVRrQFYRSS 144 Amphimedon queenslandica
EFA05823     120 T-CYKRI-HATgDFKRRR 135 red flour beetle
XP_002612505 127 RgEYVRVAHVFkGFYRDR 144 Florida lancelet
Q9DAR0       150 R-DYGHVSHVKtDFYRKN 166 house mouse
A4QMS7       115 R-DFGRANHVQaDFYRKN 131 human
XP_003443825 105 R-QYARVACIKsEIYMKN 121 Nile tilapia
XP_002665577 104 R-SFARVAHIRsDFYNKN 120 zebrafish
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