3V69


Conserved Protein Domain Family
MOEP19
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pfam16005: MOEP19 (this model, PSSM-Id:406415 is obsolete and has been replaced by 464969)
KH-like RNA-binding domain
MOEP19 is a family of mammalian KH-like RNA-binding motifs. The family is expressed during early embryogenesis. It appears to effect an early form of molecular asymmetry within the murine oocyte cytoplasm. The family marks a defined cortical cytoplasmic domain in oocytes and provides evidence for mammalian oocyte polarity and a form of pre-patterning that persists in zygotes and early embryos through the morula stage.
Links
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Statistics
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PSSM-Id: 406415
Aligned: 25 rows
Threshold Bit Score: 85.384
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3V69_A        44 KLPKWFHVECLEDPKRLYVEPRLLEIMFGKDGEHIPHLESMLHTLIHVNVWGP-ERRAEIWIFGPPPFRRDVDRMLTDLA 122
2_pfamImport   1 ILPWLNVLEDLIDPKVLEVPPWLLEPMFGPDRSRISFFEKVGKTMIELQTSES-SAHTEIVVYGDLTYRARTTWMLQCLA 79 
ACJ74003      10 IPPWVKVPEDLKDPEVLQVQTRLLEAMFGPDGSRIPYIEQVSKAMLELKALES-SDLTEVVVYGSYMYKLRTKWMLQSMA 88  rabbit
XP_235194     10 IPPWVKVPEDLKDPEVFQVHTLVLKSLFGPQGSRMPHIEQVSRAMFELKILES-SGLTEVLIYGSCNHKLRAKWMLQSMA 88  Norway rat
XP_013848085  11 ILSWVGAPEDFTEPEVFQVQTRLLEALFGPEGSRIPYVEKVSKVMLEMKALES-SDLTEVMVYGPYLYKFRTKWMLQSMA 89  pig
4_pfamImport   1 QQPWWMVPENFDTPMVVYLEEEQEEQIFGHNDAHLRCIEVHSQTLIQLESWFTaRGQTRVTIVGPPRARQWLMDMIWSLG 80 
ELK00156      35 EEPWWINPENFYLPLVFYMEEDQEERIFGRLDTDLHCIEVHSHTFIQLEGWFTaTGQTRVTIVGPPEARQWLFLMILSMG 114 black flying fox
XP_004770790  32 TQQYWCKFKHFLKPSVLNVEARLLEKIFGPSRVLLPGFEREFKVVLQMRKPNS-EGKVEIFILGRRRYRKRAKRLIRILT 110 domestic ferret
XP_025781765  29 kRPYWFHSEYLKSPKAVHLEAWLVEAIFGRGGEHIPHVECVSQTLLHVNHWDP-EGEAEILIFGRPYYQKDVSKMIMNLA 107 puma
XP_001112378  29 KRFSWFHSEFLKNPKVVRLEVWLVEKIFGRDRERIPHVQGMSQILIHVNRLDP-NGEAEILVFGRPSYQEDTIKMIMNLA 107 Rhesus monkey

3V69_A       123 HYCRMK 128
2_pfamImport  80 ERHRRQ 85 
ACJ74003      89 EWHRQR 94  rabbit
XP_235194     89 ERYRLR 94  Norway rat
XP_013848085  90 EWHCQR 95  pig
4_pfamImport  81 NW---- 82 
ELK00156     115 SWDLDq 120 black flying fox
XP_004770790 111 Tkprrk 116 domestic ferret
XP_025781765 108 DYHRQL 113 puma
XP_001112378 108 DYHRQL 113 Rhesus monkey
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