Conserved Protein Domain Family
Sharpin_PH
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pfam16764: Sharpin_PH (this model, PSSM-Id:407032 is obsolete and has been replaced by 465263)
Sharpin PH domain
This PH domain is found at the N-terminus of sharpin and is involved in dimerization.
Links
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Statistics
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PSSM-Id: 407032
Aligned: 11 rows
Threshold Bit Score: 160.705
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_005996845  23 PGPEMVLMWVrvrlsQSGTRPLFVgSAPVEETLRLQLSMEAERPGEFRLAIRSEsgaspGSSQTI-----VEFNLREIAY 97  coelacanth
XP_022519054  29 AGCSTVLMSVrvsvcHSGVRPLCL-PGASDEAVRLQLSMDPGKAGEFRLALRACggaaaPRSVTI-----AEFDLKTVRY 102 Mexican tetra
XP_023603658  14 PGSSTVLLTV-----HAAVRPLAAgPDAEAQLRRLQLSADPERPGRFRLELLGA-----GPGAVG-----LEWPLESVSY 78  little brown bat
XP_532352    469 PGPAAVLLAV-----QATVRPLGAgPDAEAQLRRLQLSADPERPGRLRLQLLGA-----GPGAGG-----SEWPLESVSY 533 dog
XP_005000937  14 SSSARILLAV-----HAVVRPQRAgPGAEAPLRRLQLSTDPERPGRLRLQLQGS-----GPEAVN-----LEWPLESVSY 78  domestic guinea...
Q91WA6        14 PASPVVLLAV-----HAAVRPLGAgQDAEAQPRKLQLIADPERPGRFRLGLLGT-----EPGAVS-----LEWPLEAICY 78  house mouse
XP_005316105  13 PGSAAVLLAV-----HAAVRPLGAgSNAETQLRRLQLSADPERPGRFRLELRGA-----GPGAVS-----LEWPLESISY 77  thirteen-lined ...
XP_001333481   5 TGCSTVLMSV-----RVSVRPLPV----GSDSLRLQLSMNPNRAGLFTLTLRHTdr--gGRSVSL-----AEFDLRSVQY 68  zebrafish
XP_015209658  29 GGCNTVLMSVrvsvcHSGIRPLCL-PGAGDESLRLQLSMDPGRAGEFRLALRDAsasaaGRSVSI-----VEFDLRDVQY 102 spotted gar
XP_022533873   2 AGGLTVLMSVrvr------avLSSgAAAGSESLRLQLSMNPERPGDFHLSLRDTps-sgHIR-SL-----AEFELRTVRY 68  Mexican tetra
XP_014890190  33 PGCQTVLMSVrvsvcHSGVRPLCL-PGAGDESLRLQLSMDPGKSGEFRLAIQST-----SGTGQSvtineFDL--RSINY 104 sailfin molly

XP_005996845  98 EVKNHTCHELIVLSRPEERMAFQFEDEREAQKWWTVLSSSLREAQKA 144 coelacanth
XP_022519054 103 EVKTPQSHELSLATPPHDRITFNFRSEQEAQAWATVVMSSLREAHRV 149 Mexican tetra
XP_023603658  79 TVRGPSQHELQPPPGGPGALSLRFLNPQEAQRWAALVRGATAEGHNG 125 little brown bat
XP_532352    534 TVRGPSRHELQPPPGGPGALSLHFLDARDARRWAALVRRAAMEGRDG 580 dog
XP_005000937  79 TICSPSQHELQPPPGGPGTLSLHFLNSEEAQRWAALVQGASAEGQNG 125 domestic guinea pig
Q91WA6        79 TVRGPNQHELQPPPGGPGTFSVHFLDPEEAQQWAALVRDATAEGQNG 125 house mouse
XP_005316105  78 TIRGPSQHELQPPPGGPGTLSLRFLNTQEAQQWAALLRGATAEGQNG 124 thirteen-lined ground squirrel
XP_001333481  69 ELKSPRCHELRLLKPPHDCLSFSFRSEQEAQEWATVVMSSLRESHRV 115 zebrafish
XP_015209658 103 EVKSLRCHELSLVTPPHDRITFNFRDEREAQEWATVVTSSLREAHRV 149 spotted gar
XP_022533873  69 EIKSPRCHELCVIKPPHETYSFTFRSEQEAQEWATVMLSSLREAHRv 115 Mexican tetra
XP_014890190 105 EVKSPKCHELISVAPPCDRISFNFSSEQEAEGWATVVMSSLREAHRa 151 sailfin molly
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