6N22,4APX


Conserved Protein Domain Family
ECD

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pfam18432: ECD 
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Extracellular Cadherin domain
This is an extracellular cadherin (EC) domain which can be found at the N-terminal region of Protocadherin 15 (Pcdh15). Pcdh15 features exceptionally long extracellular domains containing 11 ECs. These repeats are structurally similar, but not identical in sequence, often featuring linkers with conserved calcium-binding sites that confer mechanical strength to them.
Statistics
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PSSM-Id: 408229
Aligned: 3 rows
Threshold Bit Score: 202.628
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6N22_A    10 DCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPDPTIELSLKDNVDYWVLLDPVKQMLFLNSTGRVLDRDPPMN 89 
ABC79290  31 DCKLARTGPPATIVPIDEESRNGTILVDNMLIKGTAAGPDPTIELSLKDNVDYWVILDPISQRLYLNSTGRVLDRDPPMS 110
4APX_B    11 DCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPDPTIELSLKDNVDYWVLLDPVKQMLFLNSTGRVLDRDPPMN 90 
6N22_A    90 IHSIVVQVQCVNKKVGTVIYHEVRIVVRDR 119
ABC79290 111 IQSIVVQVQCVNKKVGTIINHEVRIVVRDR 140
4APX_B    91 IHSIVVQVQCVNKKVGTVIYHEVRIVVRDR 120
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