Conserved Protein Domain Family
Shugoshin_C
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pfam07557: Shugoshin_C 
Shugoshin C terminus
Shugoshin-like proteins contain this conserved sequence at the C terminus, which is rich in basic amino-acids. Shugoshin (Sgo1) protects Rec8 at centromeres during anaphase I (during meiosis) so that sister chromatids remain tethered. Sgo2 is a paralogue of Sgo1 and is involved in correctly orienting sister-centromeres.
Links
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Statistics
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PSSM-Id: 462207
Aligned: 67 rows
Threshold Bit Score: 27.8311
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EDS44024      94 GRPARSArvKAIKNLKEPTLNSKMRQ 119
XP_016656864 414 SRPSRSA--TKNINYKEKGLGGKLRR 437
XP_009122907 377 GRPSRQAt-GKIKSYKEVSLKDKMRR 401
Q0WTB8       444 GRPSRHAa-EKVQSYREVSLRVKMRR 468 thale cress
XP_006361700 271 GRPSREAa-KRVQSYKEIPVNIKMRR 295
EEF29596     193 FRPKRQVa-DKVQSYKEIPLNVKMRR 217
RCV10047     412 RRSLRRAa-EKVVSYKEIPLNVKMRR 436
XP_003536280 367 GRPLRRTv-EKIVSYKEVPVNRKMRR 391
XP_004982963 291 GRPLRQAr-ERVTSYKEMPLHVKLRR 315
EFH58927     490 GRPSRQAa-EKIKSYKEPSLKEKMRG 514
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