2GA5,1EKG


Conserved Protein Domain Family
mito_frataxin
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TIGR03422: mito_frataxin 
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frataxin
Frataxin is a mitochondrial protein, mutation of which leads to the disease Friedreich's ataxia. Its orthologs are widely distributed in the bacteria, associated with the ISC system for iron-sulfur cluster assembly, and designated CyaY. This exception-type model allows those examples of frataxin per se that score above the trusted cutoff to the CyaY equivalog-type model (TIGR03421) to be named appropriately.
Links
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Statistics
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PSSM-Id: 132463
Aligned: 27 rows
Threshold Bit Score: 139.678
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2GA5_A        21 KYHEEADDYLDHLLDSLEELSEAHPDCi-pDVELSHGVMTLEI-PAFGTYVINKQPPNKQIWLASPLSGPNRFDLL---- 94  baker's yeast
AAQ88214      56 EYEHVSERDMETLNESLEIFCEDFGNGn-wEIEYSSGVLNLTL-PPYGTYVLNKQPPNLQIWMSSPVSGPSRFEYI---- 129 Cryptococcus ne...
XP_001204076  49 QFEKIVDEALDHLSEFFEILGDSEKCPadfDVLYSSGVLTVAFgQEHGTYVINKQTPNKQIWLSSPTSGPKRYDYI---- 124 Strongylocentro...
Q9W385        72 TYERVCSDTLDALCDYFEELTENASELqgtDVAYSDGVLTVNLgGQHGTYVINRQTPNKQIWLSSPTSGPKRYDFV---- 147 fruit fly
Q8HXX9        94 TYERLAEETLDSLAEFFEDLADKPYTFedyDVSFGSGVLTVKLgGDLGTYVINKQTPNKQIWLSSPSSGPKRYDRT---- 169 crab-eating mac...
Q9TY03        24 EYETAADSTLERLSDYFDQIADSFPVSeqfDVSHAMGVLTVNVsKSVGTYVINKQSPNKQIWLSSPMSGPKRYDLE---- 99  Caenorhabditis ...
BAD53291      91 EYHKLADETIHDLLEKLEEYGDSL-QMdgfDIDYGNQVLTLRL-GELGTYVVNKQAPNRQIWLSSPVSGPSRFDWDap-- 166 Japanese rice
Q9ZR07        80 EFHKLANFTINHLLEKIEDYGDNV-QIdgfDIDYGNEVLTLKL-GSLGTYVLNKQTPNRQIWMSSPVSGPSRFDWDrd-- 155 thale cress
XP_625012     92 QFEKVSDETLTSLTEYFDELVEQAIHLsdaDVSYGDGVLTIKFgDTHGTYVINRQSPNRQIWLSSPKSGPKRYDFI---- 167 honey bee
XP_843696     65 AYNTAADTFLERVESALETIGDTDTLE---DVNLAGGVLVIET-TSRGTFVLNKQAPNVQLWLSSPLSGPHHYDMTtsat 140 Trypanosoma bru...

2GA5_A        95 -N----GEWVSLR-NGTKLTDILTEEVEK 117 baker's yeast
AAQ88214     130 -N----GSWVHHRkEGVKLGELLSGELKE 153 Cryptococcus neoformans var. neoformans
XP_001204076 125 -N----KRWIYVH-DGMAIHDLLSEEISK 147 Strongylocentrotus purpuratus
Q9W385       148 -GtvaaGRWIYKH-SGQSLHELLQQEIPG 174 fruit fly
Q8HXX9       170 -G----KNWVYSH-DGVSLHELLGAELTK 192 crab-eating macaque
Q9TY03       100 -Ee---GKWTYAH-DGEQLDSLLNREFRK 123 Caenorhabditis elegans
BAD53291     167 -----tNCWIYRR-TGANLVELLEKEIGE 189 Japanese rice
Q9ZR07       156 -----aNAWIYRR-TEAKLHKLLEEELEN 178 thale cress
XP_625012    168 -D----GKWIYKY-DRKTLHELLDDEIPA 190 honey bee
XP_843696    141 gS----VEWRADA-DGHSLEERLEKELSD 164 Trypanosoma brucei brucei TREU927
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