4OFD,4OFD


Conserved Protein Domain Family
IgI_2_KIRREL3-like
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cd05759: IgI_2_KIRREL3-like 
Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
The members here are composed of the second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2). This protein has five Ig-like domains, one transmembrane domain, and a cytoplasmic tail. Included in this group is mammalian Kirrel (Neph1), Kirrel2 (Neph3), and Drosophila RST (irregular chiasm C-roughest) protein. These proteins contain multiple Ig domains, have properties of cell adhesion molecules, and are important in organ development.
Links
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Statistics
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PSSM-Id: 409416
Aligned: 9 rows
Threshold Bit Score: 165.317
Created: 18-Sep-2007
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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  next features
Conserved site includes 4 residues -Click on image for an interactive view with Cn3D
Feature 1:Ig strand A [structural motif]
Evidence:
  • None
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1         ####                                                                           
4OFD_A       110 ETRIDGGPVILLQAGTPYNLTCRAFNa-kPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTC 188 house mouse
4OFD_B       110 ETRIDGGPVILLQAGTPYNLTCRAFNa-kPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTC 188 house mouse
CAG02866     104 NPVINGGPVVSLRAGDPLNLTCHADNa-kPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYLSPSNIETGQQIIC 182 Tetraodon nigro...
Q96J84       122 DTRIDGGPVILLQAGTPHNLTCRAFNa-kPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTC 200 human
Q6UWL6       125 APQVLGGPSVSLVAGVPANLTCRSRGdarPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVESTLTLTPFSHDDGATFVC 204 human
Q8BR86       149 DPIILGGPVISLRAGDPLNLTCHADNa-kPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVC 227 house mouse
CAM60090     121 EPVIEGSPEILLTAGVPYNMSCVSRGa-kPASVIEWQKDGLPIEGAVSTTEVLPDRKRVTTRSYLPIQPLDTDTGKNFTC 199 zebrafish
NP_001079957 123 DPMIPGSPVANVLLDVPYNLTCLASVa-kPAAEITWFRDGKKLDWAIYTKELLSDGKSEGSASSLLITPSLADTGSSYTC 201 African clawed ...
NP_001092814 119 DPIVEGGPVVRLKAHTPHNLTCRASGa-kPAAEITWYRDGEIMQNAIYSKSLMEDGKRETAVSMLPMVPEDSDSGRTYTC 197 zebrafish

Feature 1                           
4OFD_A       189 RSMNEAIPNGKETSIELDV 207 house mouse
4OFD_B       189 RSMNEAIPNGKETSIELDV 207 house mouse
CAG02866     183 KASNKAVPNGKETSVTIDI 201 Tetraodon nigroviridis
Q96J84       201 RSMNEAIPSGKETSIELDV 219 human
Q6UWL6       205 RARSQALPTGRDTAITLSL 223 human
Q8BR86       228 RATNKAIPGGKETSVTIDI 246 house mouse
CAM60090     200 VATNLAVPMGKRATITLNV 218 zebrafish
NP_001079957 202 RVRNEALPEGREKSVTLSV 220 African clawed frog
NP_001092814 198 RVLNPAAPAGRQTSVTINV 216 zebrafish

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