2QZ7,2QNG


Conserved Protein Domain Family
TerD_like
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cd06974: TerD_like 
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Uncharacterized proteins involved in stress response, similar to tellurium resistance terD
Tellurium resistance terD like proteins. This family is composed of uncharacterized proteins involved in stress response, such as the tellurium resistance proteins, chemical-damaging agent resistance proteins, and general stress proteins from a variety of organisms. The tellurium resistance proteins are homologous terA,-D,-E,-F,-Z,-X gene products, which confer tellurium resistance mediated by plasmids. Currently, the biochemical mechanism of tellurium resistance remains unknown. The family also contains several ter gene homologues, YceC, YceD, YceE, for which there is no clear evidence for any involvement in the tellurium resistance. A putative cAMP-binding protin CABP1 shows a significant similarity to the terD protein and is also included in this family.
Links
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Statistics
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PSSM-Id: 132992
Aligned: 176 rows
Threshold Bit Score: 60.0024
Created: 8-Jan-2008
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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putative metal
Conserved site includes 3 residues -Click on image for an interactive view with Cn3D
Feature 1:putative metal binding site [ion binding site]
Evidence:
  • Structure:2QZ7: Streptomyces coelicolor A3(2) Sco6318 binds Na+.
    - View structure with Cn3D
  • Structure:2QNG: Streptomyces avermitilis Unknown Function Protein Sav2460 binds Ca2+.
    - View structure with Cn3D
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                      # #                                               
2QZ7_A        23 LKRVDVRLKWdpspw----------drpphHLDIIATTYAadaphgrpVYVVQFDKRSPdg----tINXSRhsrtgq--- 85  Streptomyces co...
XP_812572    313 LSDVRFGVGWng----------------ehDLDAFMVMLDenn---cyLDHLHPKQTRLhsiyphvARHSGdaingf--g 371 Trypanosoma cru...
ZP_02207025  470 TNAVRAFIWWtnmdkcdf----gsyddgrvDIDLSAAIFDenw---nyMEHVSYTNLKSek---ykACHSGdivnggpvd 539 Coprococcus eut...
ZP_02210780  488 NKKIRLFLHWvent-------------rntDLDLSIVLYDedf---yeIDDVSYMNLKTn-----gCVHSGdvrsap--a 544 Clostridium bar...
CAG87655     466 KNILRMFIHWig-----------------dDIDLSALFLSedl---ntQSHIAFTNLKDd-----fAWHSGdivnap--g 518 Debaryomyces ha...
XP_453342    516 SKVIRLFLYWeniketqg-----aahegrvDVDLSCLQLSdnf---enKGEIAYYNLANg-----aVTHSGdftda---- 578 Kluyveromyces l...
XP_001310232 341 PKQIKFGLGWsg----------------skDLDSYGFIVSkdy---kvIGYVSGASKSKfs----yIKHMGdaasgs--- 394 Trichomonas vag...
XP_002244361 199 FNHVIFDLFWgyps------------hgcdYLDASCLLFSgs----sfVAVIDYDDTSYhs---gvIHHSGdvmdav--- 256 Florida lancelet
XP_001629809 171 FDQVIFDLYWgyps------------hgqdYLDASVLLYSgn----cfLEVLDFRHQKCnvs-pgaIRHSGdvmddn--- 230 starlet sea ane...
NP_627918     16 VTHLSIGVSWdptagssggvlgklrrktgtDLDLIAVAMQggd--pvrLAGLDSLDPMGng----sLLHSGdnqtgh--- 86  Streptomyces co...

Feature 1             #                                                                          
2QZ7_A        86 gfgfvEEXTFELDRlsp---siARVIVGVAIHqdngh---ktfddVSNTGVVVAEGy-----------rELLTDGFerv- 147 Streptomyces co...
XP_812572    372 ttgdeEFIDLMTYRmpp---evRTIIFGATYVesfgnstgtvksiFDVPKLYLRLQn------------RTAERPNsfe- 435 Trypanosoma cru...
ZP_02207025  540 gdgvsEFLDVDVDSvvr--ygaRYVVYQVYSYtgqt------yadMPHAMFGWMERadvnsgeiyepktVEQKMDLta-- 609 Coprococcus eut...
ZP_02210780  545 pkggtEYVDINLDKine---qcRYISVCINAYthek------fyeLQECFVGYMDLnkklkt-pynpscVKFKADLts-- 612 Clostridium bar...
CAG87655     519 pdgasEFIDIDLKKaqe--fgkRYVCMDVRVFcgps------fleHEQCFAGFMLRkepqsgeifepltVRCKFDIts-- 588 Debaryomyces ha...
XP_453342    579 tngaaEFIDVKLDDikeafpetRYIAVTVNSYtgq-------kfnTFTAKAGFMIRdnisge-hfepktVEQKFDLls-- 648 Kluyveromyces l...
XP_001310232 395 edkdaESIVVNLTEvpd---evGTIAIFATYEngt-------flqVQNIYMRVCTTidk-------kekELMYLPVvak- 456 Trichomonas vag...
XP_002244361 257 rrqghHTINVKLKEipk---hvTHLFFTLSAWdspn------iskYPNPSLRFFEAsnk--------skQLCRDQMsha- 318 Florida lancelet
XP_001629809 231 nrlghHTINVTLKSipp---hiNKLFFTLSAWnspn------iskYKNPSLKFYDAsyp--------dkQLCSDSMeha- 292 starlet sea ane...
NP_627918     87 gdgddETVTVEFARlps---aiTSIVFVAAAYkkgs-----sfqkARNISFKVYDAtg---------gsSEQVADIwpsl 149 Streptomyces co...

Feature 1                                                            
2QZ7_A       148 -agaTAATVAEFTRna--sgAWEFREAVRGFdsd---------pvlFATEXG 187 Streptomyces coelicolor A3(2)
XP_812572    436 --vdRWNIHYEVEDeierrkMWKKNKEKNKLekh----------gfVHRTYV 475 Trypanosoma cruzi strain CL Brener
ZP_02207025  610 --nsTACIPVIFDCvkr-efIWCDMNLSLTGvht---------higGNNVES 649 Coprococcus eutactus ATCC 27759
ZP_02210780  613 --etTVSLPFIIDIasn-qiVWCDIEYTSLGdinniitnsnrntmvVKSILD 661 Clostridium bartlettii DSM 16795
CAG87655     589 --kgRSADICLFDMktr-emIWIDTMINHGQtansla----nntasSVYIIR 633 Debaryomyces hansenii
XP_453342    649 --asRFNIPMVLDLyen-tiIWLDLAISQNKiynvnl----hektpLVGSLA 693 Kluyveromyces lactis NRRL Y-1140
XP_001310232 457 -rrqNSLLFGILYRtp--kgSWDLFPAAKLFegkds-----hdigeYCNEFF 500 Trichomonas vaginalis G3
XP_002244361 319 -aysQAIVMCSVSRkt---gVWKIDSLGTLSrgnak------nyepLKDTIR 360 Florida lancelet
XP_001629809 293 -aysQAIIMCSLCKid---eVWKVFSLRKISqgnak------nygpIQTTIG 334 starlet sea anemone
NP_627918    150 lsqdNGCAVAKAVRvg---gTWKLEVVNETGkikq-------gdehALMRFA 191 Streptomyces coelicolor A3(2)

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