Conserved Protein Domain Family
Elongin_A

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cl06096: Elongin_A Superfamily 
RNA polymerase II transcription factor SIII (Elongin) subunit A
This family represents a conserved region within RNA polymerase II transcription factor SIII (Elongin) subunit A. In mammals, the Elongin complex activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin is a heterotrimer composed of A, B, and C subunits of 110, 18, and 15 kilodaltons, respectively. Subunit A has been shown to function as the transcriptionally active component of Elongin.
Links
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Taxonomy: Eukaryota
Statistics
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Accession: cl06096
PSSM Id: 414655
Name: Elongin_A
Created: 8-Feb-2008
Updated: 24-Nov-2020
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