Conserved Protein Domain Family
PP2C_C

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cl06733: PP2C_C Superfamily (this model, PSSM-Id:323586 is obsolete)
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Protein serine/threonine phosphatase 2C, C-terminal domain
Protein phosphatase 2C (PP2C) is involved in regulating cellular responses to stress in various eukaryotes. It consists of two domains: an N-terminal catalytic domain and a C-terminal domain characteristic of mammalian PP2Cs. This domain consists of three antiparallel alpha helices, one of which packs against two corresponding alpha-helices of the N-terminal domain. The C-terminal domain does not seem to play a role in catalysis, but it may provide protein substrate specificity due to the cleft that is created between it and the catalytic domain.
Links
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Taxonomy: Metazoa
Statistics
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Accession: cl06733
PSSM Id: 323586
Name: PP2C_C
Created: 8-Feb-2008
Updated: 5-Dec-2016
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