Conserved Protein Domain Family
Swi3

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cl06829: Swi3 Superfamily 
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Replication Fork Protection Component Swi3
Replication fork pausing is required to initiate a recombination events. More specifically, Swi1 is required for recombination near the mat1 locus. Swi3 has been found to co-purify with Swi1 Swi3, together with Swi1, define a fork protection complex that coordinates leading- and lagging-strand synthesis and stabilizes stalled replication forks. The Swi1-Swi3 complex is required for accurate replication, fork protection and replication checkpoint signalling
Links
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Taxonomy: Eukaryota
Statistics
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Accession: cl06829
PSSM Id: 471517
Name: Swi3
Created: 8-Feb-2008
Updated: 4-Oct-2023
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