Conserved Protein Domain Family

cl07113: FAST_2 Superfamily 
FAST kinase-like protein, subdomain 2
This family represents a conserved region of eukaryotic Fas-activated serine/threonine (FAST) kinases (EC:2.7.1.-) that contains several conserved leucine residues. FAST kinase is rapidly activated during Fas-mediated apoptosis, when it phosphorylates TIA-1, a nuclear RNA-binding protein that has been implicated as an effector of apoptosis. Note that many family members are hypothetical proteins. This subdomain is often found associated with the FAST kinase-like protein, subdomain 2.
Taxonomy: Metazoa
Accession: cl07113
PSSM Id: 323767
Name: FAST_2
Created: 8-Feb-2008
Updated: 5-Dec-2016
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