Conserved Protein Domain Family
Nucleotidyl_cyc_III

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cl11967: Nucleotidyl_cyc_III Superfamily 
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Class III nucleotidyl cyclases
Class III nucleotidyl cyclases are the largest, most diverse group of nucleotidyl cyclases (NC's) containing prokaryotic and eukaryotic proteins. They can be divided into two major groups; the mononucleotidyl cyclases (MNC's) and the diguanylate cyclases (DGC's). The MNC's, which include the adenylate cyclases (AC's) and the guanylate cyclases (GC's), have a conserved cyclase homology domain (CHD), while the DGC's have a conserved GGDEF domain, named after a conserved motif within this subgroup. Their products, cyclic guanylyl and adenylyl nucleotides, are second messengers that play important roles in eukaryotic signal transduction and prokaryotic sensory pathways.
Statistics
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Accession: cl11967
PSSM Id: 448371
Name: Nucleotidyl_cyc_III
Created: 19-Oct-2009
Updated: 4-Oct-2023
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