Conserved Protein Domain Family

cl15786: CA_like Superfamily (this model, PSSM-Id:271780 is obsolete)
Cadherin repeat-like domain
Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers. This family also includes the cadherin-like repeats of extracellular alpha-dystroglycan.
Taxonomy: root
PubMed: 26 links
Protein: Related Protein
Related Structure
Accession: cl15786
PSSM Id: 271780
Name: CA_like
Created: 13-Jan-2012
Updated: 5-Sep-2014
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap