Conserved Protein Domain Family

cl17171: PH-like Superfamily 
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Pleckstrin homology-like domain
The PH-like family includes the PH domain, both the Shc-like and IRS-like PTB domains, the ran-binding domain, the EVH1 domain, a domain in neurobeachin and the third domain of FERM. All of these domains have a PH fold, but lack significant sequence similarity. They are generally involved in targeting to protein to the appropriate cellular location or interacting with a binding partner. This domain family possesses multiple functions including the ability to bind inositol phosphates and to other proteins.
Taxonomy: root
PubMed: 811 links
Protein: Related Protein
Related Structure
Accession: cl17171
PSSM Id: 418428
Name: PH-like
Created: 13-Mar-2013
Updated: 24-Nov-2020
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