Conserved Protein Domain Family

cl17245: KH-I Superfamily (this model, PSSM-Id:266583 is obsolete)
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K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that belong to different protein folds, but they share a single KH motif. The KH motif is folded into a beta alpha alpha beta unit. In addition to the core, type II KH domains (e.g. ribosomal protein S3) include N-terminal extension and type I KH domains (e.g. hnRNP K) contain C-terminal extension.
Taxonomy: root
PubMed: 36 links
Protein: Related Protein
Related Structure
Accession: cl17245
PSSM Id: 266583
Name: KH-I
Created: 13-Mar-2013
Updated: 16-Jan-2014
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