Conserved Protein Domain Family
PAXX

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cl21222: PAXX Superfamily 
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PAXX, PAralog of XRCC4 and XLF, also called C9orf142
PAXX is a set of eukaryotic proteins that belong to the XRCC4 superfamily of DNA-double-strand break-repair proteins. PAXX interacts directly with DSB-repair protein Ku and is recruited to DNA-damage sites in cells thus functioning with XRCC4 and XLF to bring about DSB repair and cell survival in response to DSB-inducing agents.
Links
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Taxonomy: Euteleostomi
Statistics
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Accession: cl21222
PSSM Id: 473797
Name: PAXX
Created: 16-Jan-2014
Updated: 4-Oct-2023
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