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single CXXC unit This is a solo version of the zf-CXXC domain with a conserved CXXCXXCX(n)C, zinc-binding motif. This is, thus far, only detected in the plant lineage in diverse chromatin proteins. Structural comparisons show that the mono-CXXC is homologous to the structural- zinc binding domain of medium chain dehydrogenases. The regular zf-CXXC domain binds nonmethyl-CpG dinucleotides. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",