6Z9A,6SLI,5FQ6,1PNZ,1FEP,2HDI,6V81,1XKW,6E4V,1XKH,6BPN,1BY3,6I96,4EPA


Conserved Protein Domain Family
Plug
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pfam07715: Plug 
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TonB-dependent Receptor Plug Domain
The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Links
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Statistics
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PSSM-Id: 462243
Aligned: 617 rows
Threshold Bit Score: 36.8633
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6Z9A_B  118 RKADLTgAVSV--VKVDEIQKQ--G-ENNPVKALQGrVPGMNIt------------------------ADGNPSGSATVR 168  Bacteroides thetaio...
Q8ABG0  120 RDIESPvSLRI--IGLQEIEKSp-GaNRDISCIVQS-YPGVAF---------------------------SPIGYRNDLI 168  Bacteroides thetaio...
Q8EXD4  160 EKEKQLmSRTK--LRFEEIKRMpgT-FGEPLRSIET-IPGVVP-------------------------VAAFGGGANNYS 210  Leptospira interrogans
Q8F179  134 RPEAPPnYVLS---QEDAIRMPg-G-FGDALKAVQS-MPGISPmyqmytgasfqsaiqtfaqatnpdkPDKPNGEKGFLV 207  Leptospira interrogans
Q8F853  182 EKDLESlSRYT--LQQEEIQRLp-GaQNDALKAIQT-LPGITAvppiglssssf----nnlvnsvgnsNPYSNSERGFLV 253  Leptospira interrogans
Q8A5R6  212 TVATQMgAVEIpmVQIKNTPSIl-G-ESDVMKAIQL-MPGVQA----------------------------GVDGSAGLY 260  Bacteroides thetaio...
Q8Y1U4   72 SPDTGS-SVYR--FDTDDIARLplGdATPLNQVLLQ-APGVVQ------------------------------DSFGQLH 117  Ralstonia solanacearum
Q8P5R5  125 DVSSVD-TRTV--VTSEQLAQL--P-LGRTAEAIALlAPGVVVns---------------------ggFDNGPLGGSLPS 177  Xanthomonas campest...
Q8P7N8  136 DVSSTS-SRSV--ITSQQLAIL--P-LGRSAEAIALlAPGAVAg-----------------------sGAFDNGSRSVVS 186  Xanthomonas campest...
Q8P341  126 DVSSVE-STTV--FTAEQMVSL--PvASDVSSVALL-APGAV--------------------------RGDSGLGAGNLA 173  Xanthomonas campest...

6Z9A_B  169 IRGIGTlnnNDPLYIIDGVPTKA----GMHELNGN--------DIESIQVLKdAASASIYGSRAANGV 224  Bacteroides thetaiotaomicron VP...
Q8ABG0  169 VRGGSP---SENRFYLDGVEIPNinhfSTQGASGGpvgilnadLIREVNFYT-GAFPTDKG-NALSSV 231  Bacteroides thetaiotaomicron
Q8EXD4  211 FRGADP---NTNLYLYDDLPILY----PFHFDGLTati--ngnLIKSMDVYT-GVLPANFN-NALGGV 267  Leptospira interrogans
Q8F179  208 MRGAGA---RANQFYFNGLPMSY----PFHADGLTsvi--nnnAIRSLELYS-GSYSARYG-FATGGI 264  Leptospira interrogans
Q8F853  254 MRGGGT---LANGYYLDGFPMSY----PYHLGDQSsvl--nnnIIKSFNVYS-GAFPVQFG-FATGGI 310  Leptospira interrogans
Q8A5R6  261 IRGGSP---DQNLILLDGTPVYN----VDHMFGFFsvf--tpeAIKKVTLFK-SSFPARFGGRLSSVI 318  Bacteroides thetaiotaomicron
Q8Y1U4  118 VRG-DH---ANLQYRINGVIIP------EPISGFGqml--dtrFANQINVLT-GALPAQYGYRTAGIV 172  Ralstonia solanacearum
Q8P5R5  178 FGGSAA---SENAYYLNGFNTTA-----ISNNLGGltl--pygAIDQQEIFT-GGYGAQFGRSNGGVI 234  Xanthomonas campestris pv. camp...
Q8P7N8  187 FGGAGV---TENAYYINGFNVSN-----PLSNLGGvsl--pygAIDQQETYT-GGYSARYG-RSTGGV 242  Xanthomonas campestris pv. camp...
Q8P341  174 SFGGSSv--AENGYYINGFDVTN-----MRTFLSFani--pfqGIGQLQIKT-GGYGAEYG-RSLGGI 230  Xanthomonas campestris pv. camp...
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