Conserved Protein Domain Family
HCNGP

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pfam07818: HCNGP 
HCNGP-like protein
This family comprises sequences bearing significant similarity to the mouse transcriptional regulator protein HCNGP. This protein is localized to the nucleus and is thought to be involved in the regulation of beta-2-microglobulin genes.
Statistics
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PSSM-Id: 462281
Aligned: 88 rows
Threshold Bit Score: 81.0373
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_014168967 157 T--Ppp--glETLSSKFDTFL-ALKRDkATHFNARLAQSGAMKNPAVMDKLMAFVGLdgtgpAQ-YGTVLPAEVWNPdae 230
XP_007874211  46 GnpS------PILEKKFEHFR-MLKER-NIHLNENLDNSTSSQNPYLLDKLINYVGI-----KDyYGSNLPEELQT---- 108
Q7RGH4       172 NkyS------EILNKKIDE-LsKLYEI-NLTINKNIINSNEYKNPGILEKIMEMFDI------DvYSSNYPPHIYNP--- 234 Plasmodium yoel...
Q8I479       144 NeyS------DILNTKIEE-LsKLYEL-NLTINKNIINSNEYKNPCILEKIMEIFQI------DvYSSNYPLHIYNP--- 206 Plasmodium falc...
XP_001613182 204 NeyS------DCLNQKIEE-LsKLYEI-NLTINKNIINSNEYKNPCILEKIMQIFQI------DvYSSNYPLNIYNP--- 266
KJE94125     152 GpcD------PALQRQIAAFIrIKQTNsGATFNQRLFASKAFRNPIIYEKLVQFCET-----DE-YGSNLVLEAHR---- 215
EFA77467     236 NdiD------EHLREKIIKLH-KMKQE-GLNFNDSLRNSIAFNNPLILEKLISFCEI-----KE-NGSNLPMFYFNP--- 298
Q54WI7       200 SqvD------FGLKEKIIRYH-KMKQD-GISINQALRNSSSFKNPSVIEKLISFCEI-----DE-LGSNYPLSQFNP--- 262 Dictyostelium d...
EEH52295     206 GecEtvmrsgDSLQTKVKRWT-ELKRA-GVRVVDRLRSTKAFRNPDFLESVVSHFEI-----EE-RATMFAKDAFDP--- 274
EFN59987     136 GecD--------PAAKVASWLhVQRTR-GKYINDEIRKSRGYRNPEFFAKMVEHLEI-----QQ-YGTSFAPEVFDP--- 197
XP_014168967 231 drTApvFPDWAYRHPLRKVQEELGRQ 256
XP_007874211 109 ------WKELETLKMTRNEEKNTSSS 128
Q7RGH4       235 --HD------FLSVDLFNEKENTTDK 252 Plasmodium yoelii yoelii
Q8I479       207 --KF------FSSLDLFNERSQENIQ 224 Plasmodium falciparum 3D7
XP_001613182 267 --HD------FLSIDLFNEKGEETDQ 284
KJE94125     216 --DR--FQEDSLYEALAQQQQDFIAE 237
EFA77467     299 --DA--TKPDEYYDKIEAKQREMEEK 320
Q54WI7       263 --HS--YPLDDYYKPLNEKQRKMDEK 284 Dictyostelium discoideum AX4
EEH52295     275 --SD--NAPEDFYDALAAAQKKENER 296
EFN59987     198 --SA--LPPEDYLDALQKEWTAEEER 219
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