2O3B


Conserved Protein Domain Family
NuiA
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pfam07924: NuiA 
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Nuclease A inhibitor-like protein
This family consists of protein sequences that are similar to the nuclease A inhibitor expressed by bacteria of the genus Anabaena (NuiA). This sequence is organized to form an alpha-beta-alpha sandwich fold, which is similar to the PR-1-like fold. NuiA interacts with nuclease A by means of residues located at one end of the molecule, including residues making up the loop between helices III and IV and the loop between strands C and D. The mechanism of inhibition of nuclease A by NuiA is as yet incompletely understood.
Links
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Statistics
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PSSM-Id: 429738
Aligned: 25 rows
Threshold Bit Score: 115.035
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2O3B_B                 7 SEILEQLKQASDGL-LFMSESEYPFEVFLWEGSa-pPVTHEIVLQQTG------HGQDAPFKVVDIDSFFSRATTP-QDW 77  Nostoc ...
jgi:Cyan7822_5915     19 NPLVTKLSKASEGL-VYISESDYPYEVIHWDNPn-vPLTKDLIAQKAN------ISEGTPCSEVAFDDFFNLDAPD-PDW 89 
jgi:Haur_4973         24 ETSVEKITAAANGL-LMMSETDAPFTPFAWDAAt--PFSPEALAN------------GQPIQTISLEQFLGNATTV-QEW 87 
CAN92081               4 EELLASLAEAAQGL-LFPSESDHELRPFRSRGD---ASSPAALLAAEG------LGAATPVEVTTAGDFFAPVIDV-PGD 72 
jgi:Cha6605_0717       4 AAIIDLLKQVTTDL-LWSSESDYPFEIVTWDRGv--AMTPTALFSKLA------NP-DAAIETISLTDLFAPVLTV-ENW 72 
CCH02257              18 tdfATQVTPLLTDL-LYPSESDEPIEVVDTYLKmaePLTVSHIKDWLM------LPPSVYVEEMPEADFWVPVTTI-EAW 89 
jgi:Oscil6304_5860     3 QSITEELANLTQDL-LWMSEADYPWEVVSYDCS---NVTPENLLEQSN------LPSDTLIKTVTIERFFAPALRE-QSW 71 
WP_015131694           6 ANLLAQLEELTPGIcLYYSDSDYTFKPIIWEVDtkgELTIENLLREVTppfdeyRPGGKIIKSANLDNYLQMIYQEaRKY 85  Calothr...
PRJNA234054:Hsw_2589 170 DPALATLRDMTTGL-VYMSEGDAPLEPVSFAAPa-gSLTDATLAQLAG------LPADTKVEKQELTYFLRNHTAD-NGV 240
EHQ30289              10 ENTQTKLENAADGL-LMMSESDYPFDYFTTTDE---VVDDNLILKLAG------KPAGTLVEKTTLDYLLRNMTNP-AS- 77 

2O3B_B                78 YEDEENAVVAKFQKLLEVIKSNLKNPQV------------YRLGE-VELDVYVIGETPAGNLAGISTKVVET 136 Nostoc sp. PCC ...
jgi:Cyan7822_5915     90 YGEEEKQEAAKQRNLMKIMKDHLTDLKV------------YRFGE-VEIAIYIVGKAANGEIIGLKTTAIET 148
jgi:Haur_4973         88 HGEAEKATVSQFQQLVEVLKAELTDIQV------------YRVGE-INIDAYIVGKDSAGNLVGLKTQLVET 146
CAN92081              73 AGDAALAEAGRYRRLVDLLERHLTDVRV------------YRVGR-VAIDVYVVGRHPSGAWLGLVTKVVET 131
jgi:Cha6605_0717      73 YEDAELAQVKRFTDLLHAIESNLADVKV------------FRVGE-VEIAIYIVGKTPDGEPIGLKTHAVET 131
CCH02257              90 FGDDEKAQAHQFQQLKETLEKLLTDRQV------------FRVGD-TEIDVYLLGKPAEGPRVGLKTKVVET 148
jgi:Oscil6304_5860    72 HNEEERATRNRFQQLFNFLNEQLNDLIV------------YRFGE-VEIDVYVLGTVEDKT-VGLKTTLVET 129
WP_015131694          86 DPDIAVEIAQIYQTVIKLLQSSLTFLEVaeirelndpnstFRI---------IFGSTKSGEWIGIapqleae 148 Calothrix sp. P...
PRJNA234054:Hsw_2589 241 LGNPELA--NRFKALQMYLKQELSGTQV------------YRLGTgPQVPVLVLGEAEGGKLQGFKTVLTET 298
EHQ30289              78 -GSVSPEIATRFSQLSTALKQELSEPEV------------YRVGD-RQIDVFILGKTNEGVIAGMRTKLIET 135
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