Conserved Protein Domain Family
DPM3

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pfam08285: DPM3 
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)
This family corresponds to subunit 3 of dolichol-phosphate mannosyltransferase, an enzyme which generates mannosyl donors for glycosylphosphatidylinositols, N-glycan and protein O- and C-mannosylation. DPM3 is an integral membrane protein and plays a role in stabilising the dolichol-phosphate mannosyl transferase complex.
Statistics
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PSSM-Id: 462416
Aligned: 86 rows
Threshold Bit Score: 62.5642
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EHY52938       1 MGRAAQTISLALLVTSAYLLLALPLLtedspipsilpTKIQVEIIPVLPFWAIISLGAYLLGRLGLGVLRFNDTEDAYRE 80 
EFN55694       1 MLRIFRLSAVGLLLLAAWAALLQQTT-----------EEPARTWVLLAPLLALVVFGAYLATALLYGVATFRTVPEEAEL 69 
XP_003060323   2 arRLFTLGAPVVAFLAVWVYLLRIGL-----------PPAQHSVVLLLPLWALVSFALYSLAVIGWSLAHFPTCAKDAEI 70 
XP_006364061   1 MKHIVKILALLLAVTAVWIGLLQTST-------------IPESYTWLLPLYLIVSLGCYGLLMVGIGLMNFPTCPQEALF 67 
XP_009401151   1 MKHILKIMALLVAVAGIWISLLETSV-------------VPRSYTWLLPVYLVVSLGCYGLLMVGVGLMLFPTCPQEASL 67 
A0DWS0         1 MSRGTNLFVAFSISGIVWIVTLfl------------sTGYVNEVAKSMPTYALILYFSYALFKVGGDLARLKDYPEEAQS 68  Paramecium tetr...
Q23W00         1 MVRKTKFIVLFLLFGLVWSFVVFSGLls--------kNKPLDTIAKALPGYLLMVFGCYSLYSIGYDLWILKEYPEDYQS 72  Tetrahymena the...
EGG25081       1 MKRYQKVTIVTIVTFLIWFVLLVDYLqf-------nlPSSIKSILPALPLWVVVTFGAYSLGSISYNLLIMSDCKEAYES 73 
Q76NT6         1 MKRYQKVFITFTFLMTFWLLLVLEKIql-------nlSPSIQSIIPFLPLYAVVCFGSYSLGVIAYNLLIMSDCKEASES 73  Dictyostelium d...
XP_003284282   1 MKRYQKVFLTFASLMAVWFLILIEKIql-------nlSEPVQSIIPFLPLYALVVFGSYSLGVIAYNLLIMSDCKEAADS 73 
EHY52938      81 LMGQIEQAKKNLDKRDV 97 
EFN55694      70 LQKDIARARADLARRGI 86 
XP_003060323  71 LQREMGVAQRELCAKGI 87 
XP_006364061  68 LQQDIVEAREFLKKKGV 84 
XP_009401151  68 LQKDIIEAKEFLKSRGV 84 
A0DWS0        69 LQKEVEEAKRFYKEKGL 85  Paramecium tetraurelia
Q23W00        73 LLKEIDEAKAFYKKNGV 89  Tetrahymena thermophila SB210
EGG25081      74 LSDEIKEAKRNLRSKGM 90 
Q76NT6        74 LFDEIKEAKESLRAKGM 90  Dictyostelium discoideum
XP_003284282  74 LYDEIKEAKESLRSKGM 90 
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