Conserved Protein Domain Family
Rab5-bind

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pfam09311: Rab5-bind 
Rabaptin-like protein
Members of this family are predominantly found in Rabaptin and allow for binding to the GTPase Rab5. This interaction is necessary and sufficient for Rab5-dependent recruitment of Rabaptin5 to early endosomal membranes.
Statistics
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PSSM-Id: 462752
Aligned: 4 rows
Threshold Bit Score: 355.429
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_012812295 524 CDMCSNYEKQLQGIQTQEAEIRDQVKKLQSMLRQVNDQLEKTLKDKKDLEDYMKQNTEETSTQISTLTIRTNQSETLLAD 603
O35550       533 CDMCSNYEKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDSSHQISALVLRAQASEVLLEE 612 Norway rat
Q19088        37 CEMCQNYEVNLTALQENERKLKEEVKAAMELNERYQLDLSNERDYRKELEKKMNELSTNCLNQVNEAAKANAKSEQRLDE 116 Caenorhabditis ...
TNM85253     528 CDMCSNYEKQLQAIQGQEAETRDQVKKLQVMLRQANEQLERTMTDKQNLEDSVQAGNKETAAKVSTLLHRVQESETLLSS 607 Takifugu bimacu...
XP_012812295 604 LQQAFTQAKRNIQDQMAVLMHSREQVSEELLRLQRDNESLQGKHSLHVSLQQAENFSLPETSEELQNLVLKYREDIISVR 683
O35550       613 LQQSFSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQLAEDFILPDTVQVLRELVLKYRENIVHVR 692 Norway rat
Q19088       117 LSAKHDKSIEVFTDQLNLARDKLQQADDDFVTLGKKYKKLLGSTRKSAQELRSEKIDMPADLDQLQFICLKNREELIETR 196 Caenorhabditis ...
TNM85253     608 LQLAFSEAKRNTQENLMVLVKSREQVADELNRLQRDNESLQGKHKLHVELQQQEGFQMPDNVQELQELVVQLRDHLVALR 687 Takifugu bimacu...
XP_012812295 684 TAADHLEEKLKAEILFLKEQIQAEQCQKENIEETLQIEIENCKEEIdileASTSSLKLELDRVKAEREQLEASLQEKTRA 763
O35550       693 TAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEI----ASISSLKAELERIKVEKGQLESTLREKSQQ 768 Norway rat
Q19088       197 AAKEHTEQQLQDEITVLRAQILEERAHREDQEVTFTAEISRLQSEL----GKINTRMVVASETIADQDS-------NIRQ 265 Caenorhabditis ...
TNM85253     688 TSFDHMEEKLKAEILFLKEQIQAEQCLKENLEDTLQVEIEGYKEEI----ASFSRLKTELEQIRVEKEQLQNGVTEKAEL 763 Takifugu bimacu...
XP_012812295 764 LQNLQTLKDSLEDQLKKETGGKASLEQLVFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQTD 834
O35550       769 LESLQEIKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQAD 839 Norway rat
Q19088       266 IRDLQTTVGELETQVQQVQNERAAVEQTAQNYKQRCTSLQQELDTSEVVQRDFVKLSQSLQIQLEKIRQSE 336 Caenorhabditis elegans
TNM85253     764 LEKLQSMKISLEQQLKDLSDTKAALEAQVLDEKAKAQRLQTELDVSEQVQKDFVKLSQTLQVQLERIRQAD 834 Takifugu bimaculatus
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