3K65


Conserved Protein Domain Family
Thrombin_light

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pfam09396: Thrombin_light 
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Thrombin light chain
Thrombin is an enzyme that cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII. Prothrombin is activated on the surface of a phospholipid membrane where factor Xa removes the activation peptide and cleaves the remaining part into light and heavy chains. This domain corresponds to the light chain of thrombin.
Statistics
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PSSM-Id: 430582
Aligned: 22 rows
Threshold Bit Score: 76.5562
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3K65_B         2 ATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGR 49 
XP_015194117 276 SAGSYKTFFNPNSFGQGEADCGIRPMFERVNKQDATEKELTESYIASR 323
XP_005169022 326 TLDQRKAFFNPRSFGNGELDCGERPLFEKINKADKNEKELLMSYTGSR 373
NP_001027864 310 LSSSKKRFFNPRTFGEGEDECGRRPLFEQKNKKDASEDELLQSYREKR 357
XP_023818208 309 LAPAKKLFFNPRTFGEGESSCGLRPLFELKSKKDAKEQELLDSYREQR 356
XP_005812182 309 LGPEKKLFFSPRSFGQGESVCGQRPLFEQKGKQDKNENELLESYREQR 356
1_pfamImport   1 LKPARKTFFSPRTFGEGESVCGERPLFEKLKKKDRNEAELLESYRQER 48 
XP_005986997 305 TTGEHKLFFNPKYFGQGENGCGLRPLFEEKNIEDNGEKELLESYIGGR 352
XP_003206466 303 VFQEFKTFFDEKTFGEGEADCGTRPLFEKKQITDQSEKELLDSYMGGR 350
XP_003214643 310 STVEHQILFNPSTFGDGEADCGVRPLFEKKKISDNSEQELLDSYQGGR 357
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