Conserved Protein Domain Family
DUF3402

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pfam11882: DUF3402 
Domain of unknown function (DUF3402)
This domain is functionally uncharacterized. This domain is found in eukaryotes. This presumed domain is typically between 350 to 473 amino acids in length. This domain is found associated with pfam07923.
Statistics
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PSSM-Id: 463384
Aligned: 62 rows
Threshold Bit Score: 341.987
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCE27603      539 PASILEAGELFSTRVRMTRAMRQMWEAREQFLQFERGWAEDd---------dDDDDdvegdhgqgdddvesllDLVDLTP 609 
Q9VZQ9        437 PQPIHEGFKTLQRHMYMSLADVQIKKEEDI-------------------------------------------------- 466  fruit fly
XP_002130558  472 PKTTKDSLKILRKHTYVPMSDLQIAKEVEM-------------------------------------------------- 501 
Q5KQ96        368 PFAISEADKLYHQHEYVSLGLLQMWQVREDYIREERGLGKSgligftngydgEEEE-----------------DAEEVEA 430  Cryptococcus ...
XP_001523697  469 PVAMIEADKILQNAVYESYSLKMLWKERDKFMQQERGYESAygk------ddNFDLeqsavk------------------ 524 
XP_002550703  465 PYAMKEADEILKKAVYESYSTKRLWKEREIFMKQERGFSDVye------------------------------------- 507 
Q59LZ8        499 PLAMREADEILRKSIYESYSIKRLWNERDYFMKQERGYADGydk------ttKNDDd----------------------- 549  Candida albicans
EGW30064      516 PLAMKEADEILKNSIYESYSIKRLWNEREKFMIQERGYVNEy-------------------------------------- 557 
XP_001383058  493 PYAIKEANEILKDSVYESYSIKRLWDERQRFMKQERGYVNEy-------------------------------------- 534 
XP_013025890  378 PKSIIEAAELLHRQTKHNVVVEQLLFEREYLRHCTLQYLLGtdf------ndAVSS------------------------ 427 
CCE27603      610 EereilrevkavqheitksnrsrkstarpiqyshteveVDFGPHPDrLSER-------------DKQRLVA--------- 667 
Q9VZQ9        467 ----------------------------------------------------------------ARNPISThedei-klt 481  fruit fly
XP_002130558  502 ----------------------------------------------------------------TKCPLTIgkqevistg 517 
Q5KQ96        431 Mmrewkyeqe--------------------emdceergDREGVKKArEKRM-------------AAKRLRR--------- 468  Cryptococcus ...
XP_001523697  525 --------------------------------pelkanTDANADTDaNTDAnsdhy---evdskNVALLQR--------- 560 
XP_002550703  508 -------------------------------------dEEGTHKDEfEYDYeqlmke-fpdrqqEIESMER--------- 540 
Q59LZ8        550 --------------------------------------DDDDDNDEfDYNFnelrqk-ypektsVIDTLER--------- 581  Candida albicans
EGW30064      558 --------------------------------------QEEQPKDEfDYDYddlkqr-fpekmdVIELLQR--------- 589 
XP_001383058  535 --------------------------------------GDEAPDELqEENYdnidygfksrsrsEIRSIRR--------- 567 
XP_013025890  428 ----------------------------------------------------------------LDFSHEKppvndptln 443 
CCE27603      668 -VERFYKDALPHLQSLVIVLLRPILVNVT---AVvTQ----QSNQ-QMQmna------------ggPMAGGRGYN---Ng 723 
Q9VZQ9        482 pAEVLYQAILPNLPQYMIALLKVLLAASP------------TSKS-KTEsinimadv-lprkmpltATQST--------- 538  fruit fly
XP_002130558  518 vTERLYQAMLPHIPQYMIALLKILLAAAP------------TSKA-KNDsiniladv-lpqemlstVVASL--------- 574 
Q5KQ96        469 -VDIIHKNTLPILHSCVIALLKLLLATVT-------------SPS-TGGgvnlqnanmppglhsptQEMPPSDKPn-aPp 532  Cryptococcus ...
XP_001523697  561 -VEQFYASSLSKLHTFVKVLIEIIKSNRI------------------ETnlnfyelelnpstsymiNSPVSQSND----- 616 
XP_002550703  541 -VELLYSRNLSRLHTIVEVLMETIKVNRL------------------DYnlnftelelnpetsiiqNKNSRRNED----- 596 
Q59LZ8        582 -IETLYSQNLCRLNTIVEVFIETIKVNRL------------------DYnlnfaelelnsktksghRDET---------- 632  Candida albicans
EGW30064      590 -VDKMYAANVSRLYTVVEVLMETIKVNRM------------------DYnlnfaelelnpetsflsRNGVPTPGDaklKs 650 
XP_001383058  568 -VEDFYSKNIVRLHTFIQVLVETIKSNRM------------------DYnlnfaewelnpetsyfnKSNTTTSENg---- 624 
XP_013025890  444 fVSKSYDDLFLHLDIFVQLSMHLFYYTSKkvnKLyIEafssSEAAmQMQsindmavadspseeisePVVKPLEKDs---- 519 
CCE27603      724 gpYGnaprgmmdqsgqtmaqeelePSPEEVDA--------------ARTREITTKAMTGILVLLLKWLRLSHVLKFEYLT 789 
Q9VZQ9        539 --------------------------KLTVDI--------------GRHKEIIVKAVSAIILLYLKHFKINHVYQFEFMS 578  fruit fly
XP_002130558  575 --------------------------RLGIDV--------------NRHREIIVKSISGMLLLLLKHFKLNHVYQFEYMS 614 
Q5KQ96        533 p------------------------tQEEIDI--------------ARHREITSKAVSAILILLLKWFKASHVLKFHLLT 574  Cryptococcus ...
XP_001523697  617 --NArsk--------------iemVLMLQLEV--------------LSVKETTCKAVTDILLNLLSWLKRSHILKSYYFS 666 
XP_002550703  597 --TKrqv---------------elVLLSQLEV--------------NNVKELTLKASTSIILLLLKWFKISHVLKSYYFS 645 
Q59LZ8        633 --IQkki---------------emVLISQLEV--------------NNAKELTLKATSSLILNLLKWFKISHILKSYYFS 681  Candida albicans
EGW30064      651 ieQTkek--------------iryVLTSQLEV--------------LNVKEITLKASTNIVLLLLKWFKISHVLKYYYLS 702 
XP_001383058  625 -kNAktr--------------ieyVLMSQLEV--------------INIKEITLKASTSIIILLLKWFKISHVLKYYYLS 675 
XP_013025890  520 --------------------------MDDLSElasgffvsgtisyfVDTCELILYSLSGLFLMMLKWFRLSHVLRSERFA 573 
CCE27603      790 QLLLDSNYIPLVLKL----FAHQDVQQVVDS-----KMDRV---EN-----------------SFFQFCNLRSKFRDKSe 840 
Q9VZQ9        579 QHLVFANCIPLVLKF----F-NQTITEYVNT-----KN------------------------------------------ 606  fruit fly
XP_002130558  615 QHLVFANCIPLVLKF----F-NQNIVAYVTT-----KN------------------------------------------ 642 
Q5KQ96        575 QLLFDSNCLLLLLKM----FGLTDISQVVTA-----HNEVE---SL-----------------NFFNYCYLECGR----- 620  Cryptococcus ...
XP_001523697  667 SLLFDQQFFSIALDYiggsFNNPNNQSTAPP-----KSDELieyEVlinqnrllnpqiklptmKFFNHCLGLRN------ 735 
XP_002550703  646 SLLFDQQFFTISLDYlsrcFNNANLQSTSTT-----KKDELteyEIlinqnklmnpkimlpkcDFFNNCLQQEV------ 714 
Q59LZ8        682 SLLFDQQFFAISLEYlsrcFNNANLQSMITTtnsrqKKDELteyEIlinqnklmnpkislpngNFFDNCLCLSLTHQEV- 760  Candida albicans
EGW30064      703 SILFDQQFFTVALDYlsrsFNNANLQSLSKDe---aKKDDLteyEIlinqnklmnpkvelptyDFFNNCLQVFPD----- 774 
XP_001383058  676 SILFDQQFFTITLDYlgngFNNSNLQSMATAd----KMEDLtdyEIlvnqnklmnpqikipkfEFFNNCIKSFP------ 745 
XP_013025890  574 KLLYDNHFLEILSRY----LSDKESSNHAERd---mKCLRG----------------------GFFSFTAK--------- 615 
CCE27603      841 sdLGNENEEsnqvgetaqtdpngqqkppheseldtaqESDDDAAPPP-IKRNRPSAkateaqdttdpkagygaearppvh 919 
Q9VZQ9            --------------------------------------------------------------------------------      fruit fly
XP_002130558      --------------------------------------------------------------------------------     
Q5KQ96        621 -------------------------------------QRPNDAA------------------------------------ 627  Cryptococcus ...
XP_001523697  736 --KSYDYQF---------------------------------------INKTFISE------------------------ 750 
XP_002550703  715 --ENQKYVL---------------------------------------INKSFIQD------------------------ 729 
Q59LZ8        761 --KYNDFNF---------------------------------------INKIFISS------------------------ 775  Candida albicans
EGW30064      775 --GNYRYKF---------------------------------------INKEFIST------------------------ 789 
XP_001383058  746 --TEYHYEL---------------------------------------INRDMTMN------------------------ 760 
XP_013025890  616 -------------------------------------SYKQFPNSPYiYSKG---------------------------- 630 
CCE27603      920 mserdakywaayqawcqaeaesnaqaearrkqredaakeesnetsnpddnepsangnpdepeqppkeqqqqqrqreeeed 999 
Q9VZQ9            --------------------------------------------------------------------------------      fruit fly
XP_002130558      --------------------------------------------------------------------------------     
Q5KQ96            --------------------------------------------------------------------------------      Cryptococcus ...
XP_001523697      --------------------------------------------------------------------------------     
XP_002550703      --------------------------------------------------------------------------------     
Q59LZ8            --------------------------------------------------------------------------------      Candida albicans
EGW30064          --------------------------------------------------------------------------------     
XP_001383058      --------------------------------------------------------------------------------     
XP_013025890      --------------------------------------------------------------------------------     
CCE27603     1000 ttsgggppRP-RVDELGYPINPLPEEEqqplITD----------FSWRNFFSLINYLRVLQKM-CKNKAHRNLFLVQYKS 1067
Q9VZQ9        607 -----------SIPLLDFPSCVIGEQPdlsgDSFvyggemsdksYSWRNVFSCINLLRILNKL-IKWKHSRVMMLVVFKS 674  fruit fly
XP_002130558  643 -----------MIPSLEFPACVIGEKSeitaETFdgvd--snsvPCWRNLFSSINLLRILNKL-VKWKHSRTMMLVVFKS 708 
Q5KQ96        628 -----------DLRPSRHPSGPLPENAe--lSND----------YSWRNFFSTINFLKVLQKV-TKHRSHRTYVMSSYKS 683  Cryptococcus ...
XP_001523697  751 --------LPkEIDE---------NNInhvqIRN----------YNANFAHILSNLLRILNKVvIKNQSQRIFALNDLKP 803 
XP_002550703  730 --------LKeEIDE---------NNVnhvyISD----------FNDNFAYILSNMLKITNKIlIKNQSQRIFTLNDLKP 782 
Q59LZ8        776 --------LPdKFDS---------NNIkhvyISN----------FNDNFAHILSDILNITNKIlIKNQSQRIFTFNDLKP 828  Candida albicans
EGW30064      790 --------LPeQVDA---------NNInhvyIKH----------YNSNFAFILSNMLKITNKIlIKNQTQRIFTLNDLKP 842 
XP_001383058  761 --------LPeTVDE---------NSVnhiyITK----------CNENFAFILSNILKIINKIlIKNVTHRIFTFNELKP 813 
XP_013025890  631 --------------------------------------------PSSRNTLITLNCLRVMGKV-CKYHINRKELLVKIDM 665 
CCE27603     1068 STILRKAL-RVPQPQLRLYTLKLVKNQVPYCGRKWRQS--NMRVITAIYLHCRPELRDEWLAGSDVDADVDSALPLEQAL 1144
Q9VZQ9        675 APILKKTL-KVRHAMMQLYVLKLLKMQTKYLGRQWRKS--NMKTMSAIYAKVRHRLNDDWAFGNDLESRPWDFQAEECTL 751  fruit fly
XP_002130558  709 APILKRAL-KVRQAMFQLYVLKLLKVQTKYLGRAWRKS--NMKTMSAIYQKVRHRLHDDWAFGNDVDAQPWDFQQEECAL 785 
Q5KQ96        684 WQILKRML-KVNQPMLQLQVLKLIKSQMPWCGRKWRQAagNMKVITSIYLNCRPELRDDWLAGTDQDTELEDAVPQDTAL 762  Cryptococcus ...
XP_001523697  804 SELFKMILiNYDTPAFSKPILKIMKKLVPYQGRKWKNV--NMDLISSIYMNCKLSMKDSWLSGRDLESDFNTSYDQEVAL 881 
XP_002550703  783 TELYKMILlNYECDPFNQPILRTLKKLIPYQGRKWKAA--NMDLISQIYLNLKLSMKDNWLSGKDLESDFNNSFDQEIAL 860 
Q59LZ8        829 SELYKMILiNYDCQSFNKPILKTLKKLIPYQGRKWKSS--NMDLISQIYLNLKLSMKDNWLSGKDLESDFNNSYDQEIAL 906  Candida albicans
EGW30064      843 SELYKMILmNYDNDAFTKPILKTLKKLIPYQGRKWKSI--NMDLISQIYLNLKLSMKDHWLSGKDLESDFNNSYDQEIAL 920 
XP_001383058  814 SELYKMILiNYDNESLSKPILKTLKKLIPYQGRKWKSI--NMDLISQIYLNLKLSVKDNWLSGKDLESDFNNSYDQEIAL 891 
XP_013025890  666 QKHLKKLL-EIPHEILKVYTLKVLKLHIPYLGIKWKQA--NMNIITDIYLHCPLNLRDSWIFQENNLETQRSSDLQDTFL 742 
CCE27603     1145 RGLTHWINLRRYPDKIa--------------------------------------------------------------- 1161
Q9VZQ9        752 RACVDRFNLRRYPEATqkcgnngtaaqnaenaqqsnmmagnngcgnngdangygnnggggngghnqqqqlndygveggfp 831  fruit fly
XP_002130558  786 RNNVERFNVRRYGKGAsaltnstniptttdey------------------------------------------------ 817 
Q5KQ96        763 RTLVQFYNLRHYIPPAplspdvshrrtssfnplyedpvlqtqhpqf---------------ghrarsdstsgtssesdvf 827  Cryptococcus ...
XP_001523697  882 RALLQFYNIRRYPSEM---------------------------------------------------------------- 897 
XP_002550703  861 RGLLQFYNVRRYPAQM---------------------------------------------------------------- 876 
Q59LZ8        907 RGLLQFYNMRNYPLQM---------------------------------------------------------------- 922  Candida albicans
EGW30064      921 RGLLQFYNMRNFPKQM---------------------------------------------------------------- 936 
XP_001383058  892 RGLLQFYNIRKYPKQM---------------------------------------------------------------- 907 
XP_013025890  743 CILIRFYHKRLYGQNC---------------------------------------------------------------- 758 
CCE27603     1162 ----------R-DL--RAALR--EEQDFFSRELE 1180
Q9VZQ9        832 sdeilthsdfAfFGhsGWWDRkvELTDYFKANYA 865  fruit fly
XP_002130558  818 --------tpvennlqnllkeevELPVEFRKSyd 843 
Q5KQ96        828 pprksssnnpA-SL--PYNPD--EMIEFWLHEYE 856  Cryptococcus neoformans
XP_001523697  898 ---------------------------------E 898 
XP_002550703  877 ---------------------------------E 877 
Q59LZ8        923 ---------------------------------N 923  Candida albicans
EGW30064      937 ---------------------------------E 937 
XP_001383058  908 ---------------------------------N 908 
XP_013025890  759 ------------------------KKLYDLNLLE 768 
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