Conserved Protein Domain Family
MRAP
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pfam15183: MRAP 
Melanocortin-2 receptor accessory protein family
This family is thought to be involved in cell trafficking. It is required for MC2R expression in certain cell types, suggesting that it is involved in the processing, trafficking or function of MC2R. MRAP may be involved in the intracellular trafficking pathways in adipocyte cells. This family of proteins is found in eukaryotes. Proteins in this family are typically between 47 and 205 amino acids in length.
Links
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Statistics
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PSSM-Id: 464550
Aligned: 6 rows
Threshold Bit Score: 131.134
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_004757558  28 MANETNASSAYdgYGYEYYLDYLDLIPVDERKLKANKYFIVITFWVSLASFVMLLFLILLYMSWSGSSQGRN---NTQHH 104
NP_001129306   1 MANRTDASVPF--TSYEYYLDYIDLIPVDEKKLKANKHSIVIALWLSLATFVVLLFFILLYMSWSGSPQVRH---SPQAY 75 
ELK15947       1 MANRTNASALY--YSFEYYLDYLDLIPVDEKKLRANKHSIVIIFWVSLAVFVVLLFLVLLYMSWSGSPQVRN---NVQHH 75 
Q68UT4         1 MANGTNASAPY--YSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYMSWSGSPQMRN---SPKHH 75  chimpanzee
AAI46207      13 QQSASNSDYT---WEYEY---Y-EIGPVSFEGLKAHKYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQDNaesSEKRF 85 
QED39647       9 qTSARRSDYV---WQYEY---YDDEEPVSFEGLKAHRYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQENpdsAEKRH 82  orange-spotted ...

XP_004757558 105 TTCPWSHSLHLPLC 118
NP_001129306  76 QVCSWTHGFHLPLC 89 
ELK15947      76 PACPWSFCLDLPLC 89 
Q68UT4        76 QTCPWSHGLNLHLC 89  chimpanzee
AAI46207      86 RMNSFVSDFGKPLE 99 
QED39647      83 RPGSCLVDIGSpqd 96  orange-spotted grouper
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