Conserved Protein Domain Family
DUF4628

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pfam15429: DUF4628 
Domain of unknown function (DUF4628)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 152 and 673 amino acids in length.
Statistics
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PSSM-Id: 464712
Aligned: 10 rows
Threshold Bit Score: 346.443
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_013131975 428 MFENS-IAQQQSpqtsrpgpss---------------------trrsaamtnSNPGSSCVDSPSS--GGQQRLKnaiNLG 483
XP_005166318   1 MFENCnAADQPK----------------------------------------SFRPSDSSALSGSktGGSQHLKnafNLG 40 
AAI25675     403 MFKNSnATQVPKlqqshsl---------------------------tqltrlAGSTSSEPSGVSIlaGSTQHLK---NLG 452
XP_023357511 417 MFENSnTAPTPKlqpsrsfph----------------------lskstalssTALGPMEPSGPGLrvGSSQHLK---NLG 471
AKH45454      23 MFENLnTTLTPKlqsshsfph----------------------lsrpgapgtITPGSGEPGGPGLrvGSSQHLR---NLG 77 
A1L170         1 MFENLnTALTPKlqasrsfph----------------------lskpvapgsAPLGSGEPGGPGLwvGSSQHLK---NLG 55  human
XP_004002755 420 MFENLnTALTPKlqssrsvph----------------------lsrptapssAAQGSAEPGGPGLwvGSSQHLK---SLG 474 sheep
XP_005994852   1 MFENSnTACTPKlqhskslsl----------------------laksssgtiSSFPATETTGPKM--GSTQHLK---NLG 53  coelacanth
XP_015211102 415 MFENSnAAHTPKlqnakfastv---------------------nkrsvasssSPATPAEVFGSGPktGSSQHLKnafNLG 473 spotted gar
XP_014896151 251 DGTSNaFSSTNGtlgsplvdqslfensiaqkqspqtsragqhstrslsvsanSNSGSTFIDSPSS--GGQQRLKnaiNLG 328 sailfin molly
XP_013131975 484 KAVGAKVNDLLRRKEPSNLGD-IGVTEVNKNVGAVWSCMEQ---LSQ--TAASSHITS--FESFPRLDPPPPSGKKRLPR 555
XP_005166318  41 KAMGAKVNDLLRRKDPSSLGD-IGVTEVNKNVEPVWASLVD---MSH--GTARNSHVS--LDSFPRLDPPPPTGKKRLPR 112
AAI25675     453 KAVGAKVNDFLRRKDNEK-GD-IGVTEVNKTVAAEWSSNDR---TCS--GNLEEGQMSknLESFPRLDPPPASVKKRIPR 525
XP_023357511 472 KAVGAKVNDFLRRKEPGNLGNtAGVMEINKNAGATLSAPDD---APP--GSWQEEERStlLEAFPRLDPPPPVTKKRTPR 546
AKH45454      78 KAVGAKVNDLLRRKESSSLGS-VGVMEINKTAEAQMPGGED---AAC--GPWLEDERSv-QEAFPLLDPPPPITRKRTPR 150
A1L170        56 KAMGAKVNDFLRRKEPSSLGS-VGVTEINKTAGAQLASGTD---AAP--EAWLEDERSvlQETFPRLDPPPPITRKRTPR 129 human
XP_004002755 475 KVVGAKVNDFLRRKEPSSLGS-VGTTEVNKTAGAQLAGGADgddGR-----------SalQEAFPRLDPPPPATRKRTPR 542 sheep
XP_005994852  54 KAVGAKVNDFLRRKETVNLGS-IGVTEVNKNVGAVLAVAEN---NSQvtTSGTGGHKS--LDIFPRLDPPPPAARKRTPR 127 coelacanth
XP_015211102 474 KAMGAKVNDLLRRKEQTSLGD-IGVTEVNKNVGAVLSSTES---SVQ--GISGHSRTS--IDWIPRLDPPPATGKKRMPR 545 spotted gar
XP_014896151 329 KAVGAKVNDLLRRKEPSHLGD-IGVTEVNKNVGAvwscmd-------klghsSASSHM--FDSFPRLDPPPPTGKKRVPR 398 sailfin molly
XP_013131975 556 ALKTTQDMMISSDPVVSSPDpvdsSSFPSSPEK-----TSPITQEE------------------------------IRne 600
XP_005166318 113 ALKTTQDMMISSDPVVASPE----SSFVSSPDK-----TSKEKAEF------------------------------QP-- 151
AAI25675     526 ALKTTQDMMISPNPILSSPEkplpATAEVPKETfsearAEKEKPLL------------------------------TNhq 575
XP_023357511 547 ALKSPQEMLISPQPVVSSLEygaeLLAGPPQEP-----PSTVPSLG------------------------------EPv- 590
AKH45454     151 ALKTTQDMLISSQPVLSNLEygteLSPGQAQDS-----PPT----A------------------------------QPv- 190
A1L170       130 ALKTTQDMLISSQPVLSSLEygtePSPGQAQDS-----APT----A------------------------------QPdv 170 human
XP_004002755 543 ALKTTQDMLISSQPVLSSLEygteLASEQPQVS-----SST-----------------------------------QPs- 581 sheep
XP_005994852 128 ALKTTQDMMISPDPVVTSTEat-dTSFTAMPECiplltQGI--------------------------------------- 167 coelacanth
XP_015211102 546 ALKTTQDMMISSDPVVTTAEvs-eTSYTSSPDKtplikKEKSLEKL---------------------------------- 590 spotted gar
XP_014896151 399 ALKTTQDMMISSDPVVASPEpadsPPFLPSPDE-----TSQgpnegskseeklpggseeqeersteitgqpslvenkads 473 sailfin molly
XP_013131975 601 EEQQQGKEEE-----------------------KRSSGPAERK-------------------PGadsetaeindnvdtvi 638
XP_005166318 152 EESNIEKPPE-----------------------ADVDSQMEKK-------------------PSvelnskptsav----- 184
AAI25675     576 QETLINGKGD-----------------------GEIVDQTESV-------------------KGn--------------- 598
XP_023357511 591 SEDNLGPESS-----------------------TEL-PGSESL-------------------PN---------------- 611
AKH45454     191 SADTSRPEST-----------------------TGMGEKGEAL-------------------PN---------------- 212
A1L170       171 PADASQPEAT-----------------------MEREERGKVL-------------------PN---------------- 192 human
XP_004002755 582 PADASQPEAT-----------------------TEVVHRGDTL-------------------PN---------------- 603 sheep
XP_005994852 168 PQDKSAKEEE-----------------------KPLTSKTNTEdrmkdinktesltdlsglqKSre-------------- 210 coelacanth
XP_015211102 591 EEEELGGETG-----------------------LPISCGPESK------------------------------------- 610 spotted gar
XP_014896151 474 ETEETKSTTDevkegeeekgsseggeeerrhqlQ---------------------------------------------- 507 sailfin molly
XP_013131975 639 ggeedgvevrsadegmdehvLQLQLS----------------------------VPDLINKDppleskakQCDVWQKAPG 690
XP_005166318 185 ---------mdernsedvdqSQMLLS----------------------------VPDLIHKD--------NLDPKKLANS 219
AAI25675     599 -------------------hLEETLS----------------------------IPDLIHKE---------------KSE 616
XP_023357511 612 --------------------GEVPLS----------------------------VPDLIHKD--------SQSDFKLRTT 635
AKH45454     213 --------------------GEVSLL----------------------------VPDLIHKN--------SQEESKRKAT 236
A1L170       193 --------------------GEVSLS----------------------------VPDLIHKD--------SQDESKLKMT 216 human
XP_004002755 604 --------------------GEVSVS----------------------------VPDLIHKD--------SQDDPKLKVT 627 sheep
XP_005994852 211 ------------------giSETILS----------------------------VPDLLNKD--------TLDLKLKTAD 236 coelacanth
XP_015211102 611 -------------------------EgenskegvqgtssglgeenqedaphllsVPDLIHKDe------iPQGRKQKPGG 659 spotted gar
XP_014896151 508 ------------------------LS----------------------------VPDLINKDpplesrakPCDVWQRASS 535 sailfin molly
XP_013131975 691 pDLRLASTPCSGKTPCRISLGEDVLLGNGAPCSk----aTGGSAEDTEHHPDLLSFE 743
XP_005166318 220 -ETRMASTPCPGKGGCRISVTEGELMENGTVDY------RTLNLDNEEPHPDLLSFE 269
AAI25675     617 iSLKVISSNHIETMSIKSSISQVELLEEEYNNVdlglwpRNATLDTDSPHPDLLSFD 673
XP_023357511 636 eWRRVSSPSLSERNGLKLSLGPLGLTEPQEDGSppp-raRTTSLDNEGPHPDLLSFE 691
AKH45454     237 eGRKSSSPGPIERNGLKLSLSPISLAESWENSSppl-qaRTSSLENEGLHPDLLSFE 292
A1L170       217 eCRRASSPSLIERNGFKLSLSPISLAESWEDGSppp-qaRTSSLDNEGPHPDLLSFE 272 human
XP_004002755 628 eCRRASSPGLMERNGLKLSLSPISLAESPEDGSppp-raRTSSVDNEGPHPDLLSFE 683 sheep
XP_005994852 237 sERKLSLP----KTHLKITLSEDDLLENGSEDSgvp-ryRNSSVDEEESHPDLLSFE 288 coelacanth
XP_015211102 660 pESGMVSTPCLGKTGQPISISEDGFLENGSVDAgm--srQRPSCVDDEHHPDLLSFE 714 spotted gar
XP_014896151 536 pDSRLASSPILGKASCRISLGEEVLLGNGAPCSk----dSGGGTEEAEPHPDLLSFE 588 sailfin molly
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