Conserved Protein Domain Family
DUF4635
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pfam15466: DUF4635 
Domain of unknown function (DUF4635)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 120 and 154 amino acids in length. There are two conserved sequence motifs: LEQ and DLE.
Links
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Statistics
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PSSM-Id: 406030
Aligned: 9 rows
Threshold Bit Score: 158.82
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EHB06786      14 TA-------VNKLPGACQNGVDtgwveqthraqfhrvenhltCPqwtrlEQEQMLFSLLVLVLYLGTGI--SGRNWEMYK 84 
XP_003756869   2 QVghvgivwKRKADSSRRIVST--------------------SI-----DKKQSILILLILFLYLTMWLsaSGKSWETSE 56 
XP_010592495  15 MV-------IQHVGNRARVGAEller------------tdsrSE-----DKKQSLLALLVLVLYLGTWI--SGRSWEVSE 68 
XP_005619271   1 MV-------TQQVGSRGRVAAElferr-----------rgsrCE-----DKKQTLLVLLILVLYVGTGI--SGRSWEVSE 55 
XP_005334216   1 MA-------TQQMESMGQVAGEllear-----------rgghCE-----DKKQTLLALLVLVLYLTTGI--SGRSWEMSE 55 
XP_003473382   1 ME-------FQQMDGRARVAAQlfeqr-----------rgshCE-----DKKQTLFTLLVLVLYLGTGI--SGRNWEVYE 55 
XP_012662078   2 VI---------QVGSRGRVAAQlleqr-----------snghCE-----DKKQTLLALLVLVLYLGTGI--SGRSWEMSE 54 
Q9DAL0         1 MT-------IQKTGCRGREAAEvveqr----------rrshhCD-----DRKQTLLALLILVLYLGMGI--SGSSWEVSG 56  house mouse
XP_002804681   1 MA-------TQQVGSRRRVAAErvaaqll------errrdshCD-----DKKQTLLALLILVLYLSTGI--SGSSWEVSE 60 

EHB06786      85 RIRECNYFQNPVASQEFEYQTSEPSKEPIKLLRNWLKNSLHVFLEKLEEEVQELEQLVQDLELWLDALLSD--PYLEEPC 162
XP_003756869  57 GIQECNFYQNHGTSKNLENQLKDQPKEPTKAMGKWLRESLDILQERLERELRVLEQQVKDLEEWLDYHLKD--LGSEEKC 134
XP_010592495  69 RIRGCNYPENTVATQGLEYQTNDGSEVPVKFIRHWLKENLHVLLEKLEEELRELEQLVRDLEEWLDAILGE--AYLEEPC 146
XP_005619271  56 RIRECNYPQNPVASQGFEYQTNEPAEEPIKVIRTWLKENLHVFLEKLEKEVQELEQLVQDLEEWLDALLGD--GHAEDPC 133
XP_005334216  56 RIRECGHPQHPVSPQGFYYHPIDPAEEPIKVLRNWVKKNLHGFLETLEEEVKELERLVRDLESWLDALLGEphPHPEEPC 135
XP_003473382  56 RIRECNFSQNPLASQGYGYHTRQPSEEPIKLLRDWLKKGLHVFLEKLEEEVQELERLVWDLELWLDALLGE--PCLEEpy 133
XP_012662078  55 RIRECKCYQNPVISQGLEYQTSEPSEEPIRVIRTWLKENLHVFLEKLEKEVRELEQLVRDLELWLDALLGEsqPYPEEPC 134
Q9DAL0        57 QTKDCNHFQNPVTPQGFEYQTKEPAEEPLRTLRKWLKINLHGFLEKLEKEVRELEQLVRDLEFWLDALLGD--LRPEDPC 134 house mouse
XP_002804681  61 RIRECNYYQNLVVSQGLEYQTDEPSEEPIKTIRNWLKENLHVFLEKLEEEVRELEQLVRDLELWLDALLGE--PHLEEHC 138

EHB06786     163 S 163
XP_003756869 135 G 135
XP_010592495 147 S 147
XP_005619271 134 S 134
XP_005334216 136 S 136
XP_003473382 134 s 134
XP_012662078 135 c 135
Q9DAL0       135 F 135 house mouse
XP_002804681 139 S 139
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