Conserved Protein Domain Family
CiPC

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pfam15800: CiPC 
Clock interacting protein circadian
CiPC is a family of proteins found in eukaryotes. The protein was identified in sheep as a gene-orthologue involved in regulation of the circadian clock. Proteins in this family are typically between 220 and 400 amino acids in length.
Statistics
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PSSM-Id: 464879
Aligned: 9 rows
Threshold Bit Score: 333.67
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_007472827  38 SDKDSGFSDGSSECLSSAEQMDSEDMLNTLSWHGEDGPR-QNSTIASNSFPALSPMVVMKNVLVKQ------G-RNSSHL 109
XP_005986588  38 SDKDSGFSDGSSEYLSAAEQTSSEDMPNFPSWILASRAQ-QNTMLVNSPFSALSPMFFMKNVLVKQ------P-ICDQLV 109
XP_015143204  17 SDKDSGYSDGSSECLSAMEHTDSEDVLNTLCWNAEDGPW-PCPVTTSGSFPALSPMVVMKNVLVKQ------G--SSSQL 87 
XP_001508288  38 SDKDSGFSDGSSECLSSAEQMDTEDMLNPLGWTGDDGSR-QKPDVGSSSFPALSPMVVMKNVLVKQ------G-SSSSEL 109
XP_003260842  38 SDKDSGFSDGSSECLSSAEQMESEDMLSALGWSREDRPR-QNSKTAKNAFPTLSPMVVMKNVLVKQ------G-SSSSQL 109
XP_006632440  37 SERDSGFSDASSEYLSAVEQTDAEDGQKTSAQSIKSKSQlPQLAVMGGGYPGLSPMIIMNNVLLKQ------AsNCPPAV 110
NP_001314832  11 TDKDS---DASSGYFSALDQTDIEDIGPTGSAALNMPTA-PRVPFITGSHPGISPMIVMNNFVLKQ------PnSTAPAL 80 
Q1LVI5        57 SEKDSGYSDTGSDSL----QTDADDRQSSASEPQNHKGSlHGSHILVSGTPELTPIFIIKDVVLKQp-----GqSGQDHI 127 zebrafish
XP_005991653  55 CESDSGFSDTSSEHLSNAEQADLPDI--KIDWSSVSSRL-DELQRVYGPFTGLTPVYIVKNVLFKQwnqanaG-LDMEYL 130 coelacanth
XP_007472827 110 Q-------------------S----WTVQPSFEVISTQPQLVFLHPS---VPPPV-----SPYP--AGEKKNDSRNYLPI 156
XP_005986588 110 Q-------------------S----WAVQPSIEVIPAQPQLLLVQPA---VPQTI-----NSRS--TRDNKADSGSYLPI 156
XP_015143204  88 Q-------------------S----WTVQPSFEVIPAQPQLVFLHPS---IPPPI-----NPHP--VGKKRNDSTNYLPI 134
XP_001508288 110 Q-------------------S----WTVQPSFEVISAQPQLVFLHPS---VPPPV-----SPFH--AGEKKSDSRNYLPI 156
XP_003260842 110 Q-------------------S----WTVQPSFEVISAQPQLLFLHPP---VPSPV-----SPCH--TGEKKSDSRNYLPI 156
XP_006632440 111 K-------------------P----WGFQPAIEVIP-QPQVVFLQPV---ISNGI-----TNTQkgPQDKRRRSQKYLPI 158
NP_001314832  81 K-------------------P----WSLNTSLDVVP-QSQLLYLQPVakcLPSGD-----STSQ--SFDKQKHSKKHAPL 129
Q1LVI5       128 L-------------------PsslsWGGGTAGGQAP--THVLLLQQPginQSTPLhilksHPQRseSKNAKKSKNTYLPI 186 zebrafish
XP_005991653 131 PqsllpftvqtnnqilhtqlA----WGGQHALSAASGQPRVLFIQQP---VAAST-----LKSP--VSNKRKERDTYLPI 196 coelacanth
XP_007472827 157 LNSYTKIAPHPGK-----------RglaLNPEERG----ETSMQKRVCTERHRTSLSSTG-PTKTSILPSDPSTPVPPSt 220
XP_005986588 157 LKSYAKIAPHPGK-----------K---LTPGKDAi---SPRDGRRGLSDSHKKQKRVETsRTSSAFRSSSAAQPFSPQ- 218
XP_015143204 135 LNSYPKIAPQPCK-----------RdhsFDLEERQ----ETSCHKRLCTEASKMENSPV---SRSTVLSTSPFAHIPVSf 196
XP_001508288 157 LNSYTKIAPHPVK-----------RslsLTLEERG----EASDRKRTCTDRHRTSLSSLG-PTKTDVSPSSPSA-VPPDl 219
XP_003260842 157 LNSYTKIAPHPGK-----------RglsLGPEEKG----TSGVQKKICTERLGPSLSSNE-PTKAGAVPSSPSTPAPPSa 220
XP_006632440 159 LKSYPKIAPHPGE-----------S-----SSERS----ASGSSERSGSASARVDRASAL-RHRRHSREKQLSR---LS- 213
NP_001314832 130 QSTFQKIAPHPAQ--------------------------EPTVDQGPGAINRRSSHSHAG-RHHRHRYEDKPFHNFPLK- 181
Q1LVI5       187 LNSYPRIAPHPSK-----------KateKPTTNRGsnteEHSLSKRVCTEEKREKVSTTT-QASKQHPHKQPENNLL--- 251 zebrafish
XP_005991653 197 LNSYPKIAPHPDKsrdnqangqtsEnhgILRTDRTa---GRSKNKRFCVEDTRVSSSESAmPKNNEVPSAAPERQEQPSp 273 coelacanth
XP_007472827 221 klAQDSVRQSLSSLVASRSLRTVPDSQEVLSSTMAKAPNLTFASPASPLGSSDSTLHGLESPMPLSM---LSAPYSPP-G 296
XP_005986588 219 --SSGTNKQQNSEILPSNRTQTNSELACNGHTGRQEEDCFTPTLESGHLQLSANAASDEALFLCPSP---SVGQIASA-Q 292
XP_015143204 197 kaPQDSNQQSSSSLMTTGKVSTLPGFHCVSADT-PKVPGLASLLPFGALQTAKCTPHENESAAQTTM---QSAVWSLP-L 271
XP_001508288 220 rlAQDSARQSSSSSLAGGALRTVHSIQLGPSGRLVKGPRLTPEVPPSPPFTVDGSGRGAENTVSPST---PAAPSSPP-A 295
XP_003260842 221 klAEDSALQGVPSLVAGGSPQTL---QPVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSP---LSANYSSPlW 294
XP_006632440 214 ----STASPTPSGLPLPLTPEPSTRKHHS--SLSKTESASSGGQPTPPASSQEAPPPARSPGLAPVP---PAAASPSR-T 283
NP_001314832 182 ----QDVSETFSGYGVDPSISSLEEIGHTVEDMHVKDSPSRLSDFQEPHTTTSPFSLCTDSFLAAFPqkfPKTSISQS-S 256
Q1LVI5       252 -----SNSHSLSRSLSAG--------HETSTDTHKNRSPCRPSSPSASLSVSSPSVSSTQIPSPPSSvdlIQTRKEPHkH 318 zebrafish
XP_005991653 274 --PTASIQQASNAAFKLDRFVQSEGYRACSSPHLG-----VPLSQSPAFSSAELSPSSAALEFPVGMl--PSGTGDRKgA 344 coelacanth
XP_007472827 297 AGDQLCHS-PETFLEQrQSKHRRFRNTLVILHRSGLLEITLKTKELIRQNQATQIELDRLKEQTQLLMEATKGN--APQA 373
XP_005986588 293 ELGPAAAT-SGQMAQQ-QSKQKRFQNTFDVLHKSGLLGITLKTKELARQNQSTQNELDQLKEQTRLFVEVLQSN--NPLV 368
XP_015143204 272 IPEETCTT-PELLLQQ-QSKCRRFQNTLVVLRRSGLLEITLKTKELIHQNQVTQAELDRLKHQTQLFIEAIKNN--APQS 347
XP_001508288 296 TVGQLRRT-LEAFPEPrQSKHRRFQNTLVVLHRSGLLEITLKTKELIRQNQATQVELDRLKEQTQLLVEAAQSN--APQA 372
XP_003260842 295 AAEHLCRS-PDIFSEQrQSKHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQVELDQLKEQTQLFIEATKSR--APQA 371
XP_006632440 284 DPDPDPEE-KGSVLEK-RNKRKRFCNTYNILHKSGLLGITLRTKELIRQNRKTQSELDRLKAHADLFVEAIRSG--DPQV 359
NP_001314832 257 DVESIPEA-----LSPsSSKRKRFCNTYNILNRSGLLGITMRTKELIRQNKRSQAQLQSLQAQTDLFLEAICSR--DPKV 329
Q1LVI5       319 CPGQKSDSgKGSHTFKgTARHRRFLNTVEILSQSGLLDITLRTQDLLRQNAATDRDIAQLRQHAQLLFQAAQAGvdAPAA 398 zebrafish
XP_005991653 345 NKGSKKHA-PGIV------KQKRFHNTVEILSKSGLLGITLKTKGLIRQNRNTQREIDELKEHTRLLCKAMQSN--DSQA 415 coelacanth
XP_007472827 374 WAKLQ 378
XP_005986588 369 LAQLL 373
XP_015143204 348 WAELE 352
XP_001508288 373 ----W 373
XP_003260842 372 WAKLQ 376
XP_006632440 360 WTKLQ 364
NP_001314832 330 WTRLQ 334
Q1LVI5       399 WEKLQ 403 zebrafish
XP_005991653 416 WLKLQ 420 coelacanth
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