Conserved Protein Domain Family
DUF4712

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pfam15830: DUF4712 
Domain of unknown function (DUF4712)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 133 and 267 amino acids in length.
Statistics
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PSSM-Id: 464899
Aligned: 8 rows
Threshold Bit Score: 275.601
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_014341968   1 MSEKLRQCRQDLAAALDRAFEDIivrpscSKSPDNSCDPKKERQRSPSPSLPNVNALIYKRCPphfsSSYTKQ------- 73 
ELK15094       1 MSEKLRRCRKELTAAIDRAFEGV------SHSPECPGRQRLEMDSAPLSFPVAVPGLPCRRHP----ACPSAA------- 63 
XP_011977548  23 MSEKLRRCRKELTAAIDRAFEGV------SHSQECSGRPRVEPDAAPLSFPLPVHRLLCRRHPl--vACSSVA------- 87 
XP_008103227   9 MSEKLNRCRKELAAAIGRAMEDL----------------SIPPLASPDSAADLSSDLPTTRTPtppnEEPSSQkgestpp 72 
XP_006171023   1 MSEKLRRCRKELTAAIDRAFEGA------SHSQEGPGPRR------PPALAPPLHRLLCRRHPl--aAC----------- 55 
Q9D9C7         1 MSEKLRRCRKELTAAIDRAFEGV------RHSQECTAQQRLD---APSLTSQPVHRLLC-RNPl--aACPSAA------- 61  house mouse
Q6ZUJ4        13 MSEKLRRCRKELTAAIDRAFEGV------SYSQECTGQQRLELSAAPLSFSLPVHRLLCRRHPl--aACSSAA------- 77  human
XP_001367907  15 MSEKLRRCRKELTAAIDRAFEGI------SHCQECPSQPKPDADASPSSFAIQMNKLLCRRYPs---AAAYVG------- 78  gray short-tail...
XP_014341968  74 ----PLLS-PCS--PSNGSLVFLPRQISADLN--NSLYSMRIPFANKENLIIHPcSLSVEDSCSRKTQCDSDVSMKENFR 144
ELK15094      64 ----PLAPvPCA--LESEGPAFAPNQTPVSAKp-QALCPQRKPLTSKENVLLHP-SILAPERQFWRAAGDGENWRKDGLR 135
XP_011977548  88 ----PFSPiPGA--LENENVAFAPNHAPVNAKp-QVLCPKRNPLSSKENILVRS-SILAPERQFWRAAGDGENWKKDSLR 159
XP_008103227  73 tvycPQVSlPVAstSEKENPLFRQNLIPVTVAp-NIQSPKREPLSSKENTWLHP-QIFIADRQFFLSLEDSER-RKQHLS 149
XP_006171023  56 ----ALATaPCA--PENDNPAFAPIHVPASTKp-QALCTQRKPLSSKENVLAHS-SLLGPERQFRKAAGAGEGWRKECLR 127
Q9D9C7        62 ----PYSGaSCA--PESENPAFGTHHIPVNSKlqQPLYPKRKPLTSKENVLMQS-SILARDRQFWRAAGDGEDWRKDSLR 134 house mouse
Q6ZUJ4        78 ----PFAAvPCA--PENENPAFATNHAPVNAKp-HALCPERKPLTSKENVLMHS-SILAPERESWRTAGEGENWRKENLR 149 human
XP_001367907  79 ----PFAPvPCA--PENENPVFVPSHLPVNVKp-HAVCPKRKPLTSKENVLIHS-SIFVPDRQFLRAAADGDGWRKESLR 150 gray short-tail...
XP_014341968 145 KDTRSYSVLETNNPSSCPSDEITKDLLDIIESTSITTLEDLTGKLEFENELNRACSRSEGSLFQEELLELF-LD-DTCSG 222
ELK15094     136 KDTEKDLKVDSNMPLSSSSQEVTKDLLDMIDHTSIRTIEELAGKLEFENELNRVCGRGEDSPFRDGAWALL-LD-ESPQK 213
XP_011977548 160 NDTEKDVKVDTSIPLSGSSQEVTKDLLDMIDHTSIRTIEELAGKLEFENELNRVCGHCEDSPFKDEAWALL-VD-ESPQK 237
XP_008103227 150 KTDERPMKSETSVSDDDAAPQNLKELADLSDNPAMWPAEKLPRKPGFENELQEV-SRLSSELFPLDASSVLdMDvSSFRK 228
XP_006171023 128 RDLERDLKVDSNMPLSSSSQEVTKDLLDMIDHTSIRTIEELAGKLEFENELNHVCGHCQDSPFKEEAWALL-GD-ESPQK 205
Q9D9C7       135 KDMERDLKADPNVLLSSSSQEVTKDLLDMIDHTSIRTIEELAGKLEFENELNRVCGHCQDSPFKEEAWALL-VD-ESPQK 212 house mouse
Q6ZUJ4       150 KDMERDLKADSNMPLNNSSQEVTKDLLDMIDHTSIRTIEELAGKIEFENELNHMCGHCQDSPFKEEAWALL-MD-KSPQK 227 human
XP_001367907 151 KDVDRYLKVEANVPLSNSNQEITKDLLDMIDHTSIRTIEELAGKLEFENELNRVCSRSEDSPFKEEVLALF-MD-ESPHK 228 gray short-tail...
XP_014341968 223 LTE-IETKVEKcRSTEDENIIETVLDMEEDYNLLSCH 258
ELK15094     214 ASDaADPGGLR-RAFDDRSVIETVLDLEEDYNLMTSF 249
XP_011977548 238 APD-ADSGGLR-QAFDDRNIVETVLDLEEDYNLMTSF 272
XP_008103227 229 VLE---------HSTEDEAIIETLLDMEEEYRLNSST 256
XP_006171023 206 ASD-ANPGGLK-QAFDEHNIIETVLDLEEDYSLMTSF 240
Q9D9C7       213 ALD-ADPGSLK-QALDDQNIVETVLDLEEDYNLMTSF 247 house mouse
Q6ZUJ4       228 ATD-ADPGSLK-QAFDDHNIVETVLDLEEDYNVMTSF 262 human
XP_001367907 229 ATE-AEASCLK-PTFDDQNIIETVLDLEEDYNLMTSF 263 gray short-tailed opossum
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