Conserved Protein Domain Family
TIC20

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pfam16166: TIC20 
Chloroplast import apparatus Tic20-like
Chloroplast function requires the import of nuclear encoded proteins from the cytoplasm across the chloroplast double membrane. This is accomplished by two protein complexes, the Toc complex located at the outer membrane and the Tic complex located at the inner membrane. The Toc complex recognizes specific proteins by a cleavable N-terminal sequence and is primarily responsible for translocation through the outer membrane, while the Tic complex translocates the protein through the inner membrane. This entry represents Tic20, a core member of the Tic complex. This protein is deeply embedded in the inner envelope membrane and is thought to function as a protein- conducting component of the Tic complex.
Statistics
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PSSM-Id: 374405
Aligned: 13 rows
Threshold Bit Score: 148.319
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KRH21904      85 RFNSKICGqAFKYHASGFRIPANAEKPEWWWRTLSCIPYLIAL----QMSSTGYYLDPFIQKFPFFQNLIFYIPGGVNRL 160
Q9ZQZ9        97 RRPIEPAR-VAKDDFFKIKLPKIAERPEWWWRTLACVPYLISL----QISDVGFYVQPFLEKHDAIGDMIYFIPGAINRW 171 thale cress
XP_002517985 125 RRSPELPR-AYKSDFFRLPFPVLAEKPEWWWRTLACLPYLISL----YMSDTGNFIQPFLEHYDYFG-LVYFVPGAVSRL 198
XP_006371609 119 RRSITPPRaMHKNELFGFRYPVLAEKPEWWWRTLACVPYLIAL----QISDTGYFIQPFLEHYDVLGDLIYFVPGAITRL 194
XP_014620582  83 RKSNTTIRqAFIYHSSGFRIPSNAEKPEWWWRTLSCVPYLLAL----QISAAGFYLEPILEKFPLFRNLVFYIPGAVNRL 158
Q8GZ79        95 RKTLLTPR-ASKDVPSSFRFPPMTKKPQWWWRTLACLPYLMPLhetwMYAETAYHLHPFLEDFEF---LTYPFLGAIGRL 170 thale cress
Q9FM67        43 RAATLVLQsKGDDSVDASD------------RIISAVCYFYPFfdgiQYGKF------IITQYQPFQILIQPLFPAIRAF 104 thale cress
XP_006384701  37 PRRLILAKsNGNDSVDTTD------------RIISAVCYFYPFfdgiQYGKY------VITQFSPIQALIQPLFPAIKVF 98 
XP_004251935  31 KRPTIRAQsKNDDSVDGPD------------RLISAITYFYPFfdgvQYGKY------VITQFAPIQTLIQPLVPAIRVF 92 
O82251        41 RRATALTTrASYTPTPATE------------RVISIASYALPFfnslQYGRF------LFAQYPRLGLLFEPIFPILNLY 102 thale cress
XP_004250099  39 TKPTT-SIsASYNPIPATD------------RLISAVAYFLPFfnglQYGRF------LFAQYPTLALPFQPILPLLSLY 99 
XP_006657858  93 RRPEVGCRaSS--SLASFSYPELTSKPRWWWRTLACVPYLLPLhnmwSYADVIYQLHTYLQGFS----LVYTFIDTMTLF 166
Q6K5Y0        79 prTQVGCRa----SLSSFSFPELETKPRWWWRTLACVPYLLPLhnmwSFADAVYQLHPYLQQFG----LFYAFIDTMALV 150 Japanese rice
KRH21904     161 PI--WFPMLYCYVAIVWVVKNKDLPLIFRFHVMMGMLLELALQI-VYTSSNFMPLI--HFpGGTLGMYYWTGVALAYIFT 235
Q9ZQZ9       172 PT--WFFMVYCYLGYMWVVKNKELPHYLRFHMMMGMLLETALQV-IWCTSNFFPLI--HF-KGRFGMYYWMAIGFTYICL 245 thale cress
XP_002517985 199 PA--YFPMVYYYIALLGVVKNKQVPHFFRFHLMMGMLLETALQV-VWYTSNFFPLI--HF-NGTYGMYYWAGVGFAYILI 272
XP_006371609 195 PV--WFSMIYCYFAYIGIVKNKDVPHFFRFHLMMGMLLETGLQI-LWYTSNFFPLI--HY-NGMFGMHYWAGVGLAYIVI 268
XP_014620582 159 PN--WFPMLYCNVAIVWVVKNKDLPLIFRFHLMMGMLLEHALQI-VWISSNFLPLI--HF-KGTLGMYYWAGVALTYIFV 232
Q8GZ79       171 PS--WFLMAYFFVAYLGIVRRKEWPHFFRFHVVMGMLLEIALQV-IGTVSKWMPLG--VY-WGKFGMHFWTAVAFAYLFT 244 thale cress
Q9FM67       105 KSfpFNGFLIFITLYFVVVRNPNFSRYVRFNTMQAIVLDVLLIFpDLLERSFNPRD--GF-GLDVVMSLDSTVFLFLLVS 181 thale cress
XP_006384701  99 KSfpLNGFLVFLTLYFVVVRNSNFSRYVRFNTMQAIVLDVLLIFpDLLERSFNPRD--GL-GLDLLMSLDSTVFLYLLVC 175
XP_004251935  93 KSfpLNGLLVFFTLYFIVVRNPNFSRYVRFNTMQAIVLDVLLIFpDLLERSFNPSD--GF-GLDLMMSFDSTVFLFLLVS 169
O82251       103 RSvpYASFVAFFGLYLGVVRNTSFSRYVRFNAMQAVTLDVLLAVpVLLTRILDPGQggGF-GMKAMMWGHTGVFVFSFMC 181 thale cress
XP_004250099 100 RSlpYASFVTFFALYLGIVRNENLNKYPRFNALQAVVLDVLLVLpMLIQRIFSPGQs-GI-GLKFTVWMHNGLFVFVVGC 177
XP_006657858 167 PG--WLLLVIFMTVYFFVVRRKWSPHFLRFHVILAILLDTGSQA-VATMCTWMPSI--VY-QGKPMQYFWMAIAFIQIFT 240
Q6K5Y0       151 PG--WLFLMIFMTVYFFVVRRKWLPHFLRYHVILAILLDTGSQA-LATMCNWNPSI--VY-QGKPMVFFWMTIAFIQIST 224 Japanese rice
KRH21904     236 MIMCIRSALLGRFVRIPLVSESA 258
Q9ZQZ9       246 LLECIRCALAGVYAQIPFMTDAA 268 thale cress
XP_002517985 273 LLQCVRCALAGGYAQMPLISDAA 295
XP_006371609 269 LLQCVRCALAGGYAHLPLVSDAA 291
XP_014620582 233 IIRCIRCALLGTFVSIPLLSESA 255
Q8GZ79       245 VLESIRCALAGMYADIPFVCDAA 267 thale cress
Q9FM67       182 LIYGFSACLFGLTPRLPLVAEAA 204 thale cress
XP_006384701 176 LIYGSTSCLFGQIPRLPIVAEAA 198
XP_004251935 170 LVYGTSSCLLGQLPRLPIVAEAA 192
O82251       182 FVYGVVSSLLGKTPYIPFVADAA 204 thale cress
XP_004250099 178 FIYGLVSSILGKTPYLPFVTEAA 200
XP_006657858 241 VLECMRCALAGMYPNVPFISHTA 263
Q6K5Y0       225 VLECMRCALAGMYPSVPFVSQTA 247 Japanese rice
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