Conserved Protein Domain Family
zf-C2H2_assoc
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pfam16606: zf-C2H2_assoc 
Unstructured conserved, between two C2H2-type zinc-fingers
This domain is found on a set of eukaryotic Zinc finger protein 536 transcriptional regulator proteins sandwiched between zf-C2H2, pfam00096 and zf-H2C2_2 pfam13465. It is not conserved between other pairs of the zinc-fingers on these sequences. It is natively unstructured, and its function is not known. The proteins recognize and bind 2 copies of the core DNA sequence 5'-CCCCCA-3'.
Links
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Statistics
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PSSM-Id: 465193
Aligned: 5 rows
Threshold Bit Score: 114.302
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_017206135  664 RKSDEDGL-HAGLEERRGSGSDQESQSVSRSTTPGSSNITEESGVGGGLSQTGSAQEDSPHPSSPSSsDMGEEAGRPTGV 742 
XP_003225480  657 RKAEDEII-QASIEERRGSGSDQESQSVSRSTTPGSSNITEESGMGGGLSQTGSAQEDSPHPSSPSSsDVGDEVGRSAGI 735 
XP_003969454  695 RRNLEEAFqQQGLDERRGSASDPESQSISRSTTPGSSNVTEESGAGGGHSQTGSVQDDSPHPSSPSS-DLGDDVAKVSGA 773 
XP_014325595  695 RRGLDEAL-HQGVDERRGSASDPESQSISRSTTPGSSNVTEESGAGGGQSQTGSIQDDSPHPSSPSS-DAGEDLAKAAVS 772 
XP_015224129  665 RKQGEEGI-HGCLDERRGSASDPESQSISRSTTPGSSNITEESGAGGGLSQTGSAQEDSPHPSSPSS-DAGEEVAKPMGV 742  spotted gar

XP_017206135  743 qQ 744 
XP_003225480  736 -Q 736 
XP_003969454  774 aP 775 
XP_014325595  773 lQ 774 
XP_015224129  743 qQ 744  spotted gar
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