Conserved Protein Domain Family
SeqA_N
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pfam17206: SeqA_N 
SeqA protein N-terminal domain
The binding of SeqA protein to hemimethylated GATC sequences is important in the negative modulation of chromosomal initiation at oriC, and in the formation of SeqA foci necessary for Escherichia coli chromosome segregation. SeqA tetramers are able to aggregate or multimerize in a reversible, concentration-dependent manner. Apart from its function in the control of DNA replication, SeqA may also be a specific transcription factor. This short domain mediates dimerization.
Links
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Statistics
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PSSM-Id: 435785
Aligned: 8 rows
Threshold Bit Score: 67.8671
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
utah:Sant_2783     1 MKTIEVDEDLYRYIAGHTQHIGESASDILRRMLKFT 36 
WP_004235631       1 MKTIDVDEELYSYIASHTQHIGESASEILRRMLNLG 36  Morganella morganii
C4K392             1 MKLIEVDEELYRYIAAHTQYIGESASEILRRMFSLT 36  Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum)
USMARC:WQG_11490   3 MKTIEVDDELYHYIASRTQVIGESSSDILRRLLRLP 38 
Q3IGV1             1 MKQIDIDDELYQYIASNTQSIGESASTILRRLLNLS 36  Pseudoalteromonas translucida TAC125
A1STA5             1 MKNIEIEDDLYKYILANIEAFGETPSQILRRLLSLP 36  Psychromonas ingrahamii 37
Q082Q5             1 MKYIEIDEELYRFIASKTERIGESASDILRRLLNLS 36  Shewanella frigidimarina NCIMB 400
B7VI46             1 MKTIEVDEDLYRFIAGQTERIGESASDILRRLLLVD 36  Vibrio atlanticus LGP32
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