Conserved Protein Domain Family

cl00092: IFab Superfamily 
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Interferon alpha, beta. Includes also interferon omega and tau. Different from interferon gamma family. Type I interferons(alpha, beta) belong to the larger helical cytokine superfamily, which includes growth hormones, interleukins, several colony-stimulating factors and several other regulatory molecules. All function as regulators of cellular activty by interacting with cell-surface receptors and activating various signalling pathways. Interferons produce antiviral and antiproliferative responses in cells. Receptor specificity determines function of the various members of the family.
Taxonomy: root
PubMed: 4 links
Protein: Related Protein
Related Structure
Accession: cl00092
PSSM Id: 320755
Name: IFab
Created: 8-Feb-2008
Updated: 19-Sep-2018
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