Conserved Protein Domain Family

cl00245: MGS-like Superfamily 
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MGS-like domain. This domain composes the whole protein of methylglyoxal synthetase, which catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The family also includes the C-terminal domain in carbamoyl phosphate synthetase (CPS) where it catalyzes the last phosphorylation of a coaboxyphosphate intermediate to form the product carbamoyl phosphate and may also play a regulatory role. This family also includes inosine monophosphate cyclohydrolase. The known structures in this family show a common phosphate binding site.
Accession: cl00245
PSSM Id: 320852
Name: MGS-like
Created: 8-Feb-2008
Updated: 19-Sep-2018
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