Conserved Protein Domain Family

cl02573: Tudor_SF Superfamily 
Tudor domain superfamily
The Tudor domain is a conserved structural domain, originally identified in the Tudor protein of Drosophila, that adopts a beta-barrel-like core structure containing four short beta-strands followed by an alpha-helical region. It binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions. Tudor domain-containing proteins may mediate protein-protein interactions required for various DNA-templated biological processes, such as RNA metabolism, as well as histone modification and the DNA damage response. Members of this superfamily contain one or more copies of the Tudor domain.
Accession: cl02573
PSSM Id: 413384
Name: Tudor_SF
Created: 8-Feb-2008
Updated: 24-Nov-2020
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