Conserved Protein Domain Family
M

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M protein repeat
This short repeat is found in multiple copies in bacterial M proteins. The M proteins bind to IgA and are closely associated with virulence. The M protein has been postulated to be a major group A Streptococcal (GAS) virulence factor because of its contribution to the bacterial resistance to opsonophagocytosis.
Statistics
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PSSM-Id: 111279
View PSSM: pfam02370
Aligned: 59 rows
Threshold Bit Score: 1e+06
Threshold Setting Gi: 126660
Created: 16-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20
                ....*....|....*....|.
gi 126660    34 VAGQTVRADHSDLVAEKQRLE 54
gi 75504676 193 QASREVSAKQQELAAAQLQLE 213
gi 126669   145 DLTKELNKTRQELANKQQESK 165
gi 75504622 132 QNKREIDKRYKEQLHKQQQLE 152
gi 1708901  134 QSQREVEKRYQEQLQKQQQLE 154
gi 126660   409 EEKQISDASRQGLRRDLDASR 429
gi 75504596 144 SHIQALESQTQDLESQTQALE 164
gi 75504596  81 TQKQALESQKQALESQKQALE 101
gi 75504596 165 SQKQALESRKQALEEQNKQLS 185
gi 126663   288 AEKAALEAEKADLEHQSQVLN 308
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