Conserved Protein Domain Family
NESP55

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pfam06390: NESP55 
Neuroendocrine-specific golgi protein P55 (NESP55)
This family consists of several mammalian neuroendocrine-specific golgi protein P55 (NESP55) sequences. NESP55 is a novel member of the chromogranin family and is a soluble, acidic, heat-stable secretory protein that is expressed exclusively in endocrine and nervous tissues, although less widely than chromogranins.
Statistics
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PSSM-Id: 115071
View PSSM: pfam06390
Aligned: 2 rows
Threshold Bit Score: 246.701
Threshold Setting Gi: 75038635
Created: 20-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116248091   1 MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALASSNARAQQR-AAQRRSFLNAHHRSaaaaaAAQVL 79
gi 75038635    1 MDRRSRPQLGRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSSTRAQQRaAAQRRTFLNAHHRS-----AAQVF 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116248091  80 PESseSESDHEHEEVEPELarPECLEYDQDDYETEtdSETEPESDIESETEIetepETEPETAPTTEPETEPEDERG--- 156
gi 75038635   76 PEP--PESDHEDTDFEPSL--PECPEYQEEEFDYE--SETESESEIESETEF----ETESDTAPTTEPETEPEDEPGpvv 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116248091 157 PRGATFNQSLTQRLHALKLQSADASPRRAQPTTQEPESASEGEEPQrgplDQDPRDPEEEPEERKEENRQPRRCKTRRPA 236
gi 75038635  146 PKRPTFHQSLTERLSALRLRSPDASPSRAPPSTQESESPRQGEEPE----DKDPRDPEESEEPKEEEKQQQHRCKPKKPT 221
                        250       260
                 ....*....|....*....|.
gi 116248091 237 rRRDQSPESPPRKGPIPIRRH 257
gi 75038635  222 -RRDPSPESPSKRGAIPIRRH 241
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