Conserved Protein Domain Family
EIF_2_alpha

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pfam07541: EIF_2_alpha 
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Eukaryotic translation initiation factor 2 alpha subunit
These proteins share a region of similarity that falls towards the C terminus from pfam00575.
Statistics
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PSSM-Id: 311477
View PSSM: pfam07541
Aligned: 187 rows
Threshold Bit Score: 56.7548
Threshold Setting Gi: 402465835
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2AHO_B       122 WEQVAWKLEAKygdPITAIeKAVKEGEKILIDAGVPEIWVKPLLEEASKHAEERKVKMSGLITVRTNEPLGVEKIKEVIS 201
gi 68052050  122 WREVWVPLEEEygeVYAAFeDAAQNGMDVLKGL-ISDEWIEALKPIIEAYVEIPTVTIDAEFEITVPKPNGIEIIKEALI 200
gi 501690295 116 iEEIENALYHEygvLFVPFeEMVTNEPSIREKVSLSKEILDALIAVAHENVKIPKVTVSGVLHLTSTKPDGVNVIRRALR 195
gi 490139556 117 phaVKEAFYTHfglLYPAFeEIVTEGDAALKKFGFSKSVNEALKTVAAENVKISKVTITGTLVLTSMKPDGVNIIRRALR 196
gi 505097915 116 lasIEDVIYKKygaFYPVFeDLVIDPETTVKKLGFSKKISETLQKVAGESVKVPHVEVTGYLILESTRPDGVEVIRKALE 195
gi 501056052 116 aTAIEDVILDKygeLYAVFeDVVLDSDATIRKLGLSKKASEALIHIAHESVKIPRVEVTGQLVLTSAESDGVMVIRNALK 195
gi 530553316 116 eKNAAEVLEEKfgtLADALdFAAAEPEQFLSDLN-NKEWASIILGYAKENLKPPMAEVRGTIKLKHNSGDGIDIIKKALQ 194
gi 500170461 116 rkiIEEAIFREygqLYPAFeDIVTTGGEAADKLNLDETIKNALITVANENVKVSRVTITGHLILTSARADGVNVIRRALR 195
gi 160338890 121 IEKLEDSIYSKydsVYDAFiEIGRNGIDSIKELKIPKKTTGVIEEICSK-IKLPSVEIRGIMEITNSKSDGIEIIRKTLL 199
gi 408364998 123 VAEIEEKILQKydyVYDAFeAVARKGPEAIQNIDLAPEIKQAIEEESNK-IQIPQVEVRGIMEISSKKPDGIEIIKNTLA 201
                         90       100       110
                 ....*....|....*....|....*....|..
2AHO_B       202 kalEnieQdyeslLNIKIYTIGAPRYRVDVVG 233
gi 68052050  201 k-aRd-rAnqekdIEVKFSYQGAPRYRIDITA 230
gi 501690295 196 sa----ePki-pdVGIDIFYIGAPKYGIKITA 222
gi 490139556 197 sa----qPki-ddVEIDLTYLGAPNYRIKVTA 223
gi 505097915 196 kasAtks----agAEIELLYLGAPTYRIKIKA 223
gi 501056052 196 ka---sdAkt-agADIELLYLGAPIYRIKVTA 223
gi 530553316 195 vgeRd---------GITITYLGAPQYRIISQA 217
gi 500170461 196 s-aQ---Pkv-enVDIDLIYVGAPKYRIKVTA 222
gi 160338890 200 -------DelkkdSTIDITYLGAPKYRLSITS 224
gi 408364998 202 g-----iEsskggATTTVTYVGAPRYRIVVTA 228
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