4KJM


Conserved Protein Domain Family
FIVAR

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pfam07554: FIVAR 
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FIVAR domain
This domain is found in a wide variety of contexts, but mostly occurring in cell wall associated proteins. A lack of conserved catalytic residues suggests that it is a binding domain. From context, possible substrates are hyaluronate or fibronectin (personal obs: C Yeats). This is further evidenced by. Possibly the exact substrate is N-acetyl glucosamine. Finding it in the same protein as pfam05089 further supports this proposal. It is found in the C-terminal part of Bacillus sp. Gellan lyase, which is removed during maturation. Some of the proteins it is found in are involved in methicillin resistance. The name FIVAR derives from Found In Various Architectures.
Statistics
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PSSM-Id: 336737
View PSSM: pfam07554
Aligned: 205 rows
Threshold Bit Score: 30.3651
Threshold Setting Gi: 81420863
Created: 28-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
4KJM_A         5 GNLQTAINDKSGTL--AsQNFLDADEQKRNAYNQAVSAA-------ETILNKQTGPNTAKTAVEQALNNVNNAKHALN 73
gi 81762503 2782 TKLDEEINKSVTTDgmTqSSIQAYENAK-RAGQTESTNA-------QNVI---NNGDATDQQIAEEKTKVEEKYNSLK 2848
gi 81842835 2583 NRLESKINETVQTDgmTqQSVENYKQAK-IKAQNESSIA-------QTLI---NNGDASDQEVSTEIEKLNQKLSELT 2649
gi 81842835 3430 LNLENKINQTVQTDgmTqQSIEAYQNAK-RVAQNESNTA-------LALI---NNGDADEQQITTETDRVNQQTTNLT 3496
gi 81842835 3597 RQLQDEIDQGTNTDg--------mTQDSVDNYNDSLSAAiiekgkvNKLLKRN----PTVEQVKESVANAQQVIQDLQ 3662
gi 81842835 3680 NRLENSINQQTDTDgmTqDSLNNYNDKL-AKARQNLEKI-------SKVL----GGQPTVAEIRQNTDEANAHKQALD 3745
gi 81762503 2866 TQLQNDIDQPTSTTgmT-STSIAAFNEKLSAARTKIQEI-------DRVLASH----PDVATIRQNVTAANAAKTALD 2931
gi 81842835 2667 NQLQANIDQKPSTDgmT-QQSVQSYERKLQEAKDKINSI-------NNVLANN----PDVNAIRTNKVETEQINNELT 2732
gi 81762503 2949 NQLQHSIDTQTSTTgmT-QDSINAYNAKLTAARNKIQQI-------NQVLAGS----PTVEQINTNTSAANQAKSDLD 3014
gi 81762503 3032 TQLEQSINQPTDTTgmT-TASLNAYNQKLQAARQKLTEI-------NQVLNGN----PTVQNINDKVTEANQAKDQLN 3097
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