Conserved Protein Domain Family
Shugoshin_C

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pfam07557: Shugoshin_C 
Shugoshin C-terminus
Shugoshin-like proteins contain this conserved sequence at the C-terminus, which is rich in basic amino-acids. Shugoshin (Sgo1) protects Rec8 at centromeres during anaphase I (during meiosis) so that sister chromatids remain tethered. Sgo2 is a paralogue of Sgo1 and is involved in correctly orienting sister-centromeres.
Statistics
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PSSM-Id: 336739
View PSSM: pfam07557
Aligned: 79 rows
Threshold Bit Score: 30.935
Threshold Setting Gi: 195585632
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20
                  ....*....|....*....|....
gi 74604595   771 PRSRRSRGAPVNYKLPSVGSKLRR 794
gi 81904326   463 LTKRRCS-TIKSYKEPTLASKLRR 485
gi 965918715  470 LRKRRCTAAVVSYKEPTLASKLRR 493
gi 532062877  220 LPKRRCT-THINYKEPTLTSKLRR 242
gi 641693537  204 LPKRRCT-VSVNYKEPTLASKLRR 226
gi 47229416   197 ARKRRCT-MAVDYTEPSLNAKLRR 219
gi 768933757  584 ARKRRCT-MVVDYKEPTLNAKLRR 606
gi 1043419120 597 SRKRRCK-VGINYAEPKLSGKLRR 619
gi 823464088  584 AAPLRRGRPAICYKEPNLHSKLRR 607
gi 303286087  534 eRARRQAGSHADYKEPSVNRKMRR 557
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