Conserved Protein Domain Family
Shugoshin_C

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pfam07557: Shugoshin_C 
Shugoshin C terminus
Shugoshin-like proteins contain this conserved sequence at the C terminus, which is rich in basic amino-acids. Shugoshin (Sgo1) protects Rec8 at centromeres during anaphase I (during meiosis) so that sister chromatids remain tethered. Sgo2 is a paralogue of Sgo1 and is involved in correctly orienting sister-centromeres.
Statistics
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PSSM-Id: 311491
View PSSM: pfam07557
Aligned: 80 rows
Threshold Bit Score: 30.9308
Threshold Setting Gi: 195585632
Created: 22-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20
                 ....*....|....*....|....
gi 74604595  771 PRSRRSRGAPVNYKLPSVGSKLRR 794
gi 296425281 445 VRASRRAKSGVNYALPNLRDKMRR 468
gi 684174429 455 GRGSRRARAAVNYAEPNLRDKMRR 478
gi 629638224 464 GRTSRRARGAVSYAEPSLRAKMRR 487
gi 398389224 461 ARPSRRARPSVNYAEPSLVAKMRR 484
gi 296828264 446 ARPSRRSRGPINYAEPSLRGKMRR 469
gi 403176901 279 SREARRARKEVNYALPSLNKKMRR 302
gi 358055878 463 AREGRRSRKQVSYALPSLRAKMRQ 486
gi 749895677 427 GRERRT-RKSVNYAEPKLNTKMRK 449
gi 588262685 285 GRPSRRARKSVNYALPSLRAKMRK 308
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