Conserved Protein Domain Family
DUF1574

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pfam07611: DUF1574 
Protein of unknown function (DUF1574)
A family of hypothetical proteins in Leptospira interrogans.
Statistics
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PSSM-Id: 311523
View PSSM: pfam07611
Aligned: 9 rows
Threshold Bit Score: 253.85
Threshold Setting Gi: 390609680
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81464612   13 LfRKKLLTVPLLFFIFALSLDRLLSSQLV--RPYTEAGAEYYFYEMKDRVLSALIk------eKSISK-ENQKTLIFFGT 83
gi 81468529    2 M-KKIYIYYPILFLGFVFCLDKVFTLEYF--QKNFIQAGNTVYYTQRKSLFEKLI--------RDKDL-EVKSLALAFGD 69
gi 81468592    1 MfRNRFLLIPFVIFLISFGIDKLISSTIF--EPYYSLSLSDLNFKHKEFLFEELKd-------YLKKK-DRKKVLVYFGN 70
gi 81464842    1 MkSKPFLWYPVLLFFAIFLFDKLFFLDQV--RDYVKQEFTYIYYDVKKELLKEIVfkygpdgeYTRNPeKKKKLMILMGS 78
gi 501356001   3 LiRNRYLFVPFLVVFLTFCLDKLLILENI--HTYFSKSLSDINYIQKNELYEDLKe-------YLSLK-DRDKVLVYFGN 72
gi 390609680   9 plmKRWLYYPLILLALLFAADKLLLLTGKpsAGAVEGSGIQLTETARIRLDNEASfvakkrgtLTGCG-SACRTVLVFGS 87
gi 501453141   1 MlKARFLFYPVFLLTFLFLVDSIFRIPYI--QTLAKIDLTAVNYEAKSDFLQKLIee----kpGVNTP-KTKKIMLVLGS 73
gi 501356884   1 MkSKPFLFYPVVLFLFIFLVDKIFLLPIF--HDEFLQAGNSVFYFQRKVLKERLL--------RDPDL-KDKKLALVFGD 69
gi 501357235   2 kikfPIVLYPFLLVLVLFLFDKIFFLPIIveNTYSWKKIERKFYELKEDLFEVMLd-------VSKKD-PSKQIGLILGS 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81464612   84 SHMGEFS-L--------DVMRKKRSDLIVYN----FSAPSAPFSYHNYNLEKILSS-GIKPDYAVLEFYPDSM------T 143
gi 81468529   70 SRAYPYSsM--------GIEQKLQKDWVLYN----FSGPQAVPAYGLYWFEKIIKQ-GLKPKLVFYVVSPEGF------D 130
gi 81468592   71 SRALLFR-N--------DYIEKKYPDWFLFN----FSVPGGSPDYYLYWLERFQSD-GVKPDFILMDESIEIF------N 130
gi 81464842   79 SRMLYFQ-N--------SDLLAFYPDWDIYN----LSSAVTTPAYYLYFLEKLIKNgGVHPDLIVIETDPFQF------N 139
gi 501356001  73 SRGLLFD-N--------EYIHKKYPGWVMFN----FSVPGGKPDYVLQWMEEFEKD-GVKPDFFLFDHSVEMF------N 132
gi 390609680  88 SRSERFN-LlkqeasitEFLAAKERDQILETqflvYAQVGAQMVVYYHAVDRLWRQ-NLIPDAIVFELGPELLelehrnN 165
gi 501453141  74 SRLLYFD-Y--------DELVSFYPDWEIYN----LSSAVTTPAYYDFQLTKILDV-GIKPDLVIMETDPNQF------N 133
gi 501356884  70 SRSYPFSeL--------GIPEPHKKDWSLYN----FSSPQGIPMNSFIQFQEILES-GVTPNFVILSLSPEAF------D 130
gi 501357235  74 SRSGEFD-S--------EMVEEFFPNTNSFN----FAAPFGPPSFQAYWLERVLKT-KLPIRYVLIEVDPLLF------S 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81464612  144 DFCNRY---PLRYSYDLSYFLRYANWFSTN--------------DWD-T-FLRSRVFRTTVFPPRFKEAMGRIKDP---- 200
gi 81468529  131 DTKGIFynpFLKYGADDDFLLKYMDQISFE--------------DRK-K-LFLDRLFAVRRINPDLKLFIKRFQEKklse 194
gi 81468592  131 SSSILTldeVLFYGLSPIFVFRHLDRYSYS--------------DLT-G-YIVKKLFHTAKNRPRWSVIRARAKDGgila 194
gi 81464842  140 KNSTTFkkaNLANSFDPIFILKYAWTFGKE--------------NVN-Y-YFANFLFGVSYNKPYIGNVIKRFKNEnsam 203
gi 501356001 133 SAASLKvdeTLTNGLNVSFVLKHFSLFSTE--------------DIS-T-LIAKRMFRAYQYRPKLEVIIARAKNK---- 192
gi 390609680 166 HGKSEF---IFSDEYDYDYY-RLLEKFGKK--------------SVS-EeARARLIFAGYALKPRPELLISDYRARp--- 223
gi 501453141 134 QNS-VFkssNLTYSFDLGYVLSNLSLFGKD--------------HVS-F-YLGRKLFAVGTYKPYLDQMWKNYKNPylen 196
gi 501356884 131 DSKGFIlspFLRMGCDKNCIETVWEDVPSK--------------EKW-Y-YFLDHVFAIRSVEFNLSLFSSRLKQGklre 194
gi 501357235 134 KSSIDY---SLNGSYDNLYILNHIDFFRSKtvdpwstkttgfsvDEAeV-YFLKKLFALYKYPLDPSAIKANNKEIeigf 209
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81464612  201 ---------------NSKE--TILAVRNLlmtesdkf-nggipnvlLTNTPPEKLEEEAIKYYNETYRY----------- 251
gi 81468529  195 y---------dpafnTDYM--VLNLKRGEqfa------------ytTFVNDPDRLEKDAVRIRNLYLST----------- 240
gi 81468592  195 kg-------ysklrsEIWE--NLKKQRGSatsd----------sspRVVLPAELLKKRSNTDFKSYLSN----------- 244
gi 81464842  204 g---------ellktMTIA--TLKSDKGNaisp----------agaYVEKDFGKIQESARKTIGWIYPS----------- 251
gi 501356001 193 ---------------DSFLypYRDLRNNLmanlksgkgsamtpgthQAVLPPELLKKSAYGDFHSYLVP----------- 246
gi 390609680 224 ----------------------------------------------QNERPQYSILEKYIRGYKDYLDSdltgklrderi 257
gi 501453141 197 v---------lgmhkSTYD--YILTHNGNglsp----------idnYMEKDSNALLQTSHRTLDWLFAS----------- 244
gi 501356884 195 y---------ksaynQEYQ--LINFTKGEylm------------ygVHENPIEKIKNDTVRIGNLYMRS----------- 240
gi 501357235 210 fpglssgitgkehkrGYID--KIKLVNRAkfgal--------pneiKFANMDLFLERDAEAMYNQYLRG----------- 268
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81464612  252 -------------ISLSLIQKKFLFQFLKTAEKNGIKVILWSPLLYEGLETRVKSAE----------F----------YS 298
gi 81468529  241 -------------FILGTTQFFFVEQFLKLAKENDVKVYLIWPKVYETYRKRYYELE----------M----------EK 287
gi 81468592  245 -------------FTFNPKMLANQADAIQIVKQMGISYAMIWVRVARPYFELYKTKK----------VstgnlnektpYE 301
gi 81464842  252 -------------YAPSEMQYEFYKKIFILQREENLKILFVRPGVSPPMEKVLDELK----------I----------PE 298
gi 501356001 247 -------------FRFSENILSFTDQSLDLAKKLNVPSAVIWVRLSLPYMDHIRHLKvsvgenkegtV----------YD 303
gi 390609680 258 gqflsmyegnykiFAVDPLMDESLRRIVKLARDKNVPMLLYKPFVHEELNRVLD------------------------KT 313
gi 501453141 245 -------------YQRSPMQFGFYEKILTRLQNENIKSVIVWPMSSPDFENLLEKES----------L----------VK 291
gi 501356884 241 -------------FVLGKSQLPYVEAFLKLTKEKNIKTLVIWPKVFPGYYSYYEKFQ----------V----------KE 287
gi 501357235 269 -------------SSLSPTQIFFFKKMLHLLEGTGIPVIIYFPAVSEPLRRKMQTDG----------LlerfnleirnQV 325
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 81464612  299 IWENIRKEILEF--KNVVSLDMNEfraQVKCKKYIDPHHLSGGCYLEPTEILVDRL 352
gi 81468529  288 SWWPKIENLAKR--YSAVPVDLNT---QTSCDLFYDASHQSIMCFLESMKLMIDDY 338
gi 81468592  302 IMIPILQKLHES--TGTSFWNMNEd-kEYHCDDFSDPGHMSPNCFNDYADFIFKRL 354
gi 81464842  299 TWSQKIKPIHDD--WKIPLIDMSKd-pYYACNSYADSGHISLDCYRPFIRFILLHY 351
gi 501356001 304 DWYPRMVGYHKE--NGIPFWNMNDd-pTYTCNEFSDAGHMSPSCYDEYTDYIFKNL 356
gi 390609680 314 PYAPAVEKYAIDlpGGSVKFHFAKq-dDYKCKFWSDASHYSTRCTPEIMHHLLRQL 368
gi 501453141 292 TWETEIDTITKN--HNFSILKLKHd-pSYTCNAFADGGHVAKDCYRGLMRSILLEY 344
gi 501356884 288 VWWNPIEVMAKQ--YGASSLNWNQ---PNTCDLFNDASHQSALCFVDQMKeiwiny 338
gi 501357235 326 SLVSKVP----N--SKFYVIDPNVd-pNWKCKDFVDSLHLSGACFPNLLPILFPKY 374
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