Conserved Protein Domain Family
AAA_2

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pfam07724: AAA_2 
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AAA domain (Cdc48 subfamily)
This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Statistics
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PSSM-Id: 311593
View PSSM: pfam07724
Aligned: 138 rows
Threshold Bit Score: 87.2512
Threshold Setting Gi: 75015142
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1UM8_A       70 LSKSNILLIGPTGSGKTL---------MAQTLAKHLDi------------PIAISDATSLTEagyvgedvENILTRLLQA 128
gi 32129621 200 NSEVTIEMDDPQQAAAGNnn------mLGQMGIDLGDslgalmpkkriqrTMPVSEAREILVre----esEKLVNNADIY 269
gi 11133033 193 NEEVTIEVEQAPKA-NPMgd------mMGQMGMDMSSmlgdmlpkkkvkrTLPVSQARKLLVqe----eeKKLVNYDDIY 261
gi 21759169 196 DEIVTVEVKEQQ---NPMldmm-rgagMDQMNGMQDAlsgmfp-akkkkrKVTVREAKKILFed----eaSKLIDADELA 266
gi 22653791 187 NHMVEIEVTDTT---PPMlemy-tnlgAEELNITLQDmfsdllpkkkklrKVTVAEAKKILEae----eaQNLIDMDEVI 258
gi 81832890 166 HLKIEIQPPKKSV---DFsegn-vppeIVRIQESLAKaflnsq-keemkkEVTVKEAKELLKie----asEALLDMETIK 236
gi 81835992 170 DLMIEIEISKKPI--SQFnden-mppdMIKVQESIFKvlnvsq--dkikkEMSVKEAKEALAye----aiESVLDAESIR 240
gi 11132784 171 SREIEIEVRKKSI---EIdsnv--ppeILRVQENLIKvfhkeq--dkvkkTLSVKEAKEALKae----isDTLLDSEAIK 239
gi 11132844 177 DRIVEIEVKEKT---VPMvgia-gppgLEELENQIKEmlsgli-pskrrrKVKVKEALQILEqe----eaEKLIDMEEVA 247
gi 32129636 208 DRQIELEVSSDGQ--GGMmqifgplgqMEEIGNIMQDlmsgmp-kkrkkrRMTIAEARKYLEqe----evQKLIDMDAVV 280
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1UM8_A      129 SDWNVQKAQKGIVFIDEIDKISRlsenrsi-trdvsgeGVQQALLKIVEGSLVNippkggrkhPEGNfiQIDTSDILFIC 207
gi 32129621 270 HDAIVRAENTGIIFIDEIDKITKggqqgs---gevsreGVQRDILPIVEGSQIS---------TKYG--PINTDHILFIA 335
gi 11133033 262 QKAMDRAGQSGIIFIDEIDKITAadkrns---agvsreGVQRDILPIVEGSTVS---------TKYG--PLSTDHILFIA 327
gi 21759169 267 AEGIHRAEQMGMIFIDEIDKIASkegggn---aqvsreGVQRDILPIVEGSQIS---------TKYG--TVNTEYILFIA 332
gi 22653791 259 EEAVKRAENDGIIFIDEIDKIAStgysag---pdvsreGVQRDLLPIIEGCTVM---------TKYG--PVKTDYILFIA 324
gi 81832890 237 AEGLRRAEEEGIIFIDEMDKIAVsqgsssr--qdpskeGVQRDLLPIVEGSTVS---------TKHG--QIKTDYILFIA 303
gi 81835992 241 AEGLRRAQENGVIFIDEIDKVAVgskdgsr--qdpskeGVQRDLLPIVEGSVVN---------TKYG--QIKTDYILFIA 307
gi 11132784 240 MEGLKRAESSGVIFIDEIDKIAVsskegsr--qdpskeGVQRDLLPIVEGSVVN---------TKYG--SIKTEHILFIA 306
gi 11132844 248 REAIYRAENFGIIFIDEIDKIAVktpgag---pgvsreGVQRDLLPILEGTTVN---------TKYG--PVKTDHILFIG 313
gi 32129636 281 KEALRKVEDSGIVFIDEIDKIAApttgaggkgpdvsreGVQRDLLPIVEGTAVS---------TKYG--VVKTDHVLFIA 349
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|
1UM8_A      208 AGAFDGLAEIIkkrttqnvlgftqekmskkeqeailhlvqthdlvtygLIPELIGRLPVL 267
gi 32129621 336 SGAFAESKPSD-------------------------------------LIAELQGRFPIR 358
gi 11133033 328 AGAFAESKPSD-------------------------------------LIPELQGRFPIR 350
gi 21759169 333 AGAFHMSKPSD-------------------------------------LIPELQGRFPIR 355
gi 22653791 325 AGAFNVAKVSD-------------------------------------LIPELQGRFPIR 347
gi 81832890 304 AGAFHLSKPSD-------------------------------------LIPELQGRFPLR 326
gi 81835992 308 AGAFHLSKPSD-------------------------------------LIPELQGRFPLR 330
gi 11132784 307 AGAFHLSKPSD-------------------------------------LIPELQGRFPLR 329
gi 11132844 314 AGAFHMAKPSD-------------------------------------LIPELQGRFPIR 336
gi 32129636 350 SGAFHVARPSD-------------------------------------LIPELQGRFPIR 372
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