5KXF


Conserved Protein Domain Family
SPOC

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pfam07744: SPOC 
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SPOC domain
The SPOC (Spen paralogue and orthologue C-terminal) domain is involved in developmental signalling.
Statistics
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PSSM-Id: 336797
View PSSM: pfam07744
Aligned: 55 rows
Threshold Bit Score: 65.8328
Threshold Setting Gi: 122061576
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5KXF_A         25 PPDSDHIWRGX-IAKGGtPVCCARCVPXGKGIETKL---------PEVVNCSARTDLNXLAkhYAVAIG----CEIVf-- 88
gi 74950636    88 FSKTNLVWQGN-IARNGkKITETLAIKISGQCSTFLnss------vemINITHRLKWEEASk-----------NVPLavf 149
gi 74990695   202 NNSNTILWKGV-LEMKNkDSLSINAYGLNGDVNNFLnnn------iknIIISHRKKMKNLPk-----------IEAIyhf 263
gi 75016015   337 TNNNEYIWKGI-LSMKNkENLNIIGHALQGNVNIFLnah------itnIVISHRKRMKSIPq-----------MEAIyyf 398
gi 124461020  457 RQDLNVFWSGF-MYRSKsHRVGVDAFCVESDVIFlqne-------qppIQMSPQIQVNYKGnfSDAKKCa--nDSFKfil 526
gi 124444195  578 EDSNATFWSGY-MNRGKqHRVGIDARMYSAAIDRn------------kINLPCNLEMSYLCsyQDAYQRaiqdQSAVlif 644
gi 549655     435 SLNCAFLYPGLgLEFTGyLNYIGASQKLRRDIFKeaig-------dgkLYVEGRLPTTTAApyLKEISCsr-aILVYqlf 506
gi 75158777   923 KQNIGHQWQGA-LSKSGvHYSTIIAQRLESDICKYIigspepvqwPVKLDMTKRTDMKNVKatFANTQPhkreVCQLi-- 999
gi 75320930   395 KQRSHPRWQGS-LSKSGlHYCSIYASRIELDACRYEhavseptgwPSRLDVTKRTDYQHVKttFSNTPPskreVCRLl-- 471
gi 156100415  414 SNVKYALWKGT-LEMKNkKNLSVIGYALNGDVKKFLnng------issIVISHRKKMKTLPk-----------IEATyyf 475
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5KXF_A         89 -fVPDREEDFASYteFLRYLSSKDR------AGV-----AKLDDGTTLFLVPP---------SDFLTDVL---------Q 138
gi 74950636   150 siHSSNNLKIEPFkeYIDYFQSKNRvtnfilIGV-----SPLGNDHNIYICAPgnplfdkhlP----------------D 208
gi 74990695   264 --eiQNEKDINIFesYKNYFNNKDR------VGL-----ASANENWHFYIIFPgtpifneilNANNNI-----------Q 319
gi 75016015   399 --eiENKQDENIFdsYKNYFNTKDR------VGL-----VSTNENWHLYIIFPgspifnqfcN----------------N 449
gi 124461020  527 --cpSDQTQHGAFqeYIDYFLDKKK------IGVaql------gnGVLYLLPP---------CEIANSIMsis------- 576
gi 124444195  645 --spAQESDIPKFseYLQYLRSKQR------AGViqt------dlYSIYVIPPgvqe------------------aqqiC 692
gi 549655     507 --psNDSESKTTFadVVDSLENKGRi-----AGIk----PKTRYEKDFYIVPSkggeipeilKDILGSHNderserfsrM 575
gi 75158777  1000 ---pAAFSDRKGLqdFITYLKQRDC------AGVikipaSSPMWARHLFILPHsq-----etCSLLSV-----------S 1054
gi 75320930   472 ---pCSNGDQKGFrdFISYLKQREC------AGVikipsVKPLWSRLLFILPPtp-----eaCGMLEL-----------P 526
gi 156100415  476 --qiENKEDESILdaYRNYFNSKDR------VGL-----SSTSDDWHMYLIFPgspifkefcNSVGGVNSfgg---gnsS 539
                         170
                  ....*....|...
5KXF_A        139 VTRqeRLYGVVLK 151
gi 74950636   209 GLTtpTLIGIVTN 221
gi 74990695   320 TNFnnTFIGVVSY 332
gi 75016015   450 NNLdnIFIGIVCY 462
gi 124461020  577 ---gleLLAIFSE 586
gi 124444195  693 NINqqEMIAIYCN 705
gi 549655     576 KSDerTLFAFVVV 588
gi 75158777  1055 PSSseCLIGLVLP 1067
gi 75320930   527 PHPteCLIALILP 539
gi 156100415  540 NNFnnIFLGVVCY 552
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