Conserved Protein Domain Family
SPOC

?
pfam07744: SPOC 
Click on image for an interactive view with Cn3D
SPOC domain
The SPOC (Spen paralogue and orthologue C-terminal) domain is involved in developmental signalling.
Statistics
?
PSSM-Id: 311609
View PSSM: pfam07744
Aligned: 56 rows
Threshold Bit Score: 66.2277
Threshold Setting Gi: 122061576
Created: 20-Jul-2016
Updated: 4-Aug-2016
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2RT5_A          4 VQLLKKYPIVWQGLLALKN-DTAAVQLHFVSGNNVLAH---RSLplseggppLRIAQRMRLEATQ--LEGVARRM-Tvet 76
gi 122171653  674 TTLPMIRESIWEGAIQLTMsSLTNVVAIFKSGEKPPVKe-wRSF--------VEIKGRVKLSAFQefVEQLPKSR-Sr-- 741
gi 75264394   532 ALSDDKGERAWDGILQLSMsSVVPVAGIFKSGEKAETSe-wPAM--------VEVKGRVRLSGFGkfIQELPKSR-Tr-- 599
gi 75116841   589 SVFIPDGERLWEGVLQLSPsTVSSVIGILRSGERTTTKe-wPIL--------LEIKGRVRLDAFEkfVRELPNSR-Sr-- 656
gi 122242471  461 LDRPSLKDWNWEGTIAKGGnPICRAKCFPVGKVMDMML---PEF--------LDCTARTGLDMLAkhYYQSS-------- 521
gi 75322984   488 HEPLLKEEWKWDGTIAKGGtPICRARCFPVGKVLNFML---PEF--------LDCTARTSLEMLSkhYYQAA-------- 548
gi 290463421  431 IRGPPDSDHIWRGMIAKGGtPVCCARCVPMGKGIETKL---PEV--------VNCSARTDLNMLAkhYAVAI-------- 491
gi 147841857  615 HVDQKKGDYVWEGLLQLNVsSMATVVCFFKSGEKASTKe-wPGF--------LEIKGRVRLDAFEkfLQELPMSR-Sr-- 682
gi 147801865 1533 aQSHSGTDYIWRGIIAKGGaTVCHARCVAIEKGLSSKL---PEI--------VNCSARTGLDLLTkhYAEAVG------- 1594
gi 145349019  271 PIDVPLPEGAWEGTVDVPGlPTLQLRAVPIGGEGAHVGdilPES--------LHIKGRVDYKAMQsfVKQVHRSStSr-- 340
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2RT5_A         77 DYCLLla-lP--CgrDQEDVVSQteslkaaFITYLQAKQAAGiinVpnPGSNQPaYVLQIFPP-------C-EFSESHLS 145
gi 122171653  742 AIMVTelcwKegS--HESGRQHLl-----qTIDSYISDERVG---L--AEPADG-IELYLCPSqg-------kTVEILSR 801
gi 75264394   600 ALMVMylayKdgI--SESQRGSLi-----eVIDSYVADQRVG---Y--AEPASG-VELYLCPTrg-------eTLDLLNK 659
gi 75116841   657 AVMVMcfvcKeeC--SKAEQENIs-----eVVDSYAKDGRVG---Y--AEPASG-VELYLCPTrg-------rTVEILNK 716
gi 122242471  522 KAWVVff-vP--G--SDADIVFYd-----eFMHYLEEKQRAA---V--SKLDDT-TTLFLVPP-------S-DFSEKVL- 576
gi 75322984   549 SSWVVff-vP--E--NDADMAAYn-----eFMNYLGDKQRAA---V--CKLGER-SSLFLVPP-------S-DFSEQVL- 603
gi 290463421  492 GCEIVff-vP--D--REEDFASYt-----eFLRYLSSKDRAG---V--AKLDDG-TTLFLVPP-------S-DFLTDVL- 546
gi 147841857  683 ATMVVrfawkegS--SEDGRANLc-----eVADSYVLDERVG---F--AEPAPG-MELYFCPP-------HtXTLEMISK 742
gi 147801865 1595 -FEVVff---lpD--SEDDFASYt-----eFLCYLGSKDRAG---V--AKLDDG-TTLFLVPP-------S-DFLSKVLK 1649
gi 145349019  341 AVTLVhissApsG--GDDAEAAMa-----kIVKQYRERKRCG---V--AKTEDG-IELYLAPRgqhadkvI-LTVDLIPG 406
                         170       180
                  ....*....|....*....|....*....
2RT5_A        146 RLAPD-----LlasiSNIspHLMIVIASV 169
gi 122171653  802 HLPKEhleslA----VSa-sSIIGVIVWR 825
gi 75264394   660 VISQEqldevK----SLd-iGLVGVVVWR 683
gi 75116841   717 IVPRNqldflK----SINddGLIGVVVWR 741
gi 122242471  577 ----------K----VPGklSISGVILRL 591
gi 75322984   604 ----------R----VPGkvSISGVILKF 618
gi 290463421  547 ----------Q----VTRqeRLYGVVLKL 561
gi 147841857  743 HLYKD-----QtetlNSTdnGLIGVVVWR 766
gi 147801865 1650 VSGPE---------------RLYGVVLKl 1663
gi 145349019  407 HVPPs--------------tGMIGMVIHP 421
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap