Conserved Protein Domain Family
Glyco_hydro_38C

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pfam07748: Glyco_hydro_38C 
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Glycosyl hydrolases family 38 C-terminal domain
Glycosyl hydrolases are key enzymes of carbohydrate metabolism.
Statistics
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PSSM-Id: 311613
View PSSM: pfam07748
Aligned: 45 rows
Threshold Bit Score: 120.999
Threshold Setting Gi: 81526010
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3CZN_A       553 KHVVMHNTLPHWREQLVDFYVSSPFVSVTDLAnnpveaqvspvwswhhdtltktihpqgsttkyriifkarvppmglaty 632
gi 81849259  630 EGAILVNSLSWSREQWIKLYDRWTKVNLNSLSgeiikkeei--------------------------------------- 670
gi 81849177  620 RSVVVFNSLVFERDDIATFDVPEDIENPAVLDgeeeiicqriddwekaiffakg-------------------------- 673
gi 81324155  625 AVVSVYNGAAFDRTELVEIPVQAGIGSQGGWLgeagrplraefdgsrwlvlaedv------------------------- 679
gi 81849795  621 EKITLWNSSTWTRPRYIEISPENPADHLAFYDennillpaqklvnntwliqhpn-------------------------- 674
gi 81857896  620 EKWTFFHPYQYDTPILVTIPKGTDERFVDQTGhglssqqtannetlvlleksip-------------------------- 673
gi 74556577  576 DKTFVFNSLSWDREEYIEADgklvkvrvpsvgfslle------------------------------------------- 612
gi 74574247  561 EEIYLFNSLNWDREEYVEINgkfykvkvpsigftafk------------------------------------------- 597
gi 81853094  608 FPIFVFNSLNWQRSEVVSVTLPPPPTNQQWQVydttgeqiisqltepstllflakdi----------------------- 664
gi 81834505  590 LPVVVFNSLATPRDAPVALPAPGNLRGARLVAvdrtgkdvpvqaagdwlhfwaa-------------------------- 643
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3CZN_A       633 vltisdskpehtsyasnlllrknptslplgqypedvkfgdpREIslrvgNG--PTLAFSEq-GLLKSIQLTQDSPHVP-- 707
gi 81849259  671 ---------------------------------epyceistLKVsennlENglVKVEFNEn-GTIARIFDKELNKEVLrd 716
gi 81849177  674 --------------------ipangyksfkiiestnkevenVSLnekeaENdfLRIKFNEe-GNIVSLFDKRAEREVLke 732
gi 81324155  680 -------------------patgaatlrfdpsagqqtsvkaFEWadgvlRTphYELAFDEa-GRLVRLYDRGLSREVLpr 739
gi 81849795  675 -------------------lpvlgaatisvketpnilgqssFNYnnkqlETpfYQIKWNEv-GQFTSIFDKKNNRQVLae 734
gi 81857896  674 --------------------fayqtisratmvaeevqmlsqVNFeerrwETpwYQLEWNDe-GQFIRMYDKLGKREWLaq 732
gi 74556577  613 -------------------------pvevrdkavinennaeYLV-----ENkyFRVRISKs-GQVLSLFDKEANREVLr- 660
gi 74574247  598 -------------------------peevkekvnvkefedyYQI-----ENkfFVLKLGKe-GKLLSLYDKEAKREVLk- 645
gi 81853094  665 ----------------psvgyrlfwlsptsppsptsptsldYVL-----ENehLRVIVDPdtGDLSSIYDKTHQREILs- 722
gi 81834505  644 -------------------gvpgighkvfwlrpadapapatTGL-----ENayLRVEVDPrtGDLASIFDKRTGRETLn- 698
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3CZN_A       708 --VHFKFLKYGV---------RSHGd---------rSGAYLFLPNGPASPvelgqpvvlvtkgkleSS--VSVGLPSVVH 765
gi 81849259  717 -eKGNELRVYEDngd---awdFSGVyedrpseifelVKSEVIV--DGPKAtikq--------nykyGDstLVQEISILEG 782
gi 81849177  733 gtLGNRLQAFEDkpmeysnwdIDIYykekm-wnvddVQSIEVVEEGPVRStlri--------erkfLEstIVQNIYVYRD 803
gi 81324155  740 gaRANELQVFEDkpkmfeawdIDLFyqekr-revtdLRKLELVECGALRAvlrl--------ewayGAsvIEQRLVVYAD 810
gi 81849795  735 ntRGNVFQLFEDkpmwhdawdIDLFyqekq-neitaLDSVEITEKGPLQFtmkq--------vlhsEKsqITQWIHFYHE 805
gi 81857896  733 gkLGNVFKRFEDkplahdawdIDLFyqeks-stvssFQGCELIENGPLRTtvlf--------rwkeDGvvIKQAIRCYRH 803
gi 74556577  661 -dKSNLLIAYENipgwadawdIEKGfedrs--feirASSSEIVNNDGIVAsikf--------tykfRRseIIQIVRVYAD 729
gi 74574247  646 -gPSNVLTFYENipgwadawdIEKGyeetn--fvvkASSSTVI--EDTVVnvky--------tykfRNseVYQIVRIYPD 712
gi 81853094  723 -gAGNQLQAFKDsgqywdawnIDPSysqhp-lpatnLKSIQWLEQGAVQNrlrv--------vrqlGEseFCQDYILQVG 792
gi 81834505  699 -gPGNRLQFFKDegqywdawnIDPDyekhp-leaptLVSLQTVEQGPVRAvvrv--------vrrfRQstFEQDLILYRD 768
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3CZN_A       766 QtimrgGAPEIRNLVDi-GSLDntEIVMRLETHIDSGDIFYTDLNGLQFIkrrrldklP------LQANYYPIPSGMFIE 838
gi 81849259  783 S-----KRIDFKTKVDwkENGK--MLRTSFNTNVYTREADCEIQFGTIKR--------PthgntsWDMAKGEICAQRWID 847
gi 81849177  804 L-----DRIDFNSYVDwkEHEV--LLKTSFPIDLNATEATYEIQYGNVKR--------PthsntsWDEARFEVCGQKWAD 868
gi 81324155  811 D-----RRIDFVTRVDwrEHQQ--LLKVAFPVEIRATEATYDIQFGNVKR--------PthwntsWDHARFETVGHQWVD 875
gi 81849795  806 S-----PEIRFETEVDwrDRNQ--LLKVAFPVDVHASEASYDIQFGNVKR--------PthwntsWDYARFETVGHQWAD 870
gi 81857896  804 T-----ARIDFATEVDwqARQQ--LLKVEFPVDIRTNEAIYDIQFGNLKR--------PthwntsWDMARFETVGHKWAA 868
gi 74556577  730 S-----RRIDFITTLRmrDREL--LVKSWFNFDLNVERAVSDIPFGVVER--------FtwsntsWDKARFEVPIQKFVD 794
gi 74574247  713 H-----RRIDFITTLRmrDREL--LLKAWFNFDVNTDKAISDIPFGVIER--------FtwqntsWDMARFEVPIQKFVD 777
gi 81853094  793 S-----PQLKIASRVNwrEKQV--LVKAAFPLNLTADFATYEIPCGAIRR--------PtqpqnpQDKAKWEVPALRWAD 857
gi 81834505  769 A-----PHLEIANRVDwqERHV--FVKAAFPLAVRSEQATYEIPFATIER--------StlrdtpARKAQWEVPALRWAD 833
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3CZN_A       839 DANt------rLTLLTGQPLGGSS-LA--SGELEIMQDR-----RLASDDERGLGqgvldnkpvlhIYRLVLEKV-NNcv 903
gi 81849259  848 LSQrd----ygVALINDSKYGHNVs----ETKIDLNLLRspgypDPNADRGEHEF-----------TYCLFPHRGdYIeg 908
gi 81849177  869 LSEgd----fgVSLLNNCKYGHDIq----DGDMRLTLLKsgthpWTETDQEEHFF-----------TYSIYPHMGtWKea 929
gi 81324155  876 LSErg----ygVSLLNDCKYGHDIk----DNVIRLSLIKsaidpDPNADQGEHLF-----------TYSLYPHAGdWAsg 936
gi 81849795  871 LSEkn----ygVSLLNDSKYGYDIk----DSTIRLTLLKaagypDPDADLGIHQF-----------TYSLYPHQGdFLdg 931
gi 81857896  869 IAEad----ygISLLNDSKYGYSIk----DNVLSLSLLKgaiypDPEADIGNHQF-----------TYALYPFQGpAFkr 929
gi 74556577  795 FSEse----ygAALLNNGKYGATLr----GSSVGLSLTKtpiypDPSTDLEEVTF-----------IYSLYPHIGdWKra 855
gi 74574247  778 LSEgn----ygVALLSEGKYGVSLr----GTSVGLSLTKtplypDPTTDLEEVTF-----------TYSLYPHIGdWRka 838
gi 81853094  858 LTAdtdkgiygVSLLNDCKYGYDSq----PQLLRLTLLRsptwpDPEADTGIHEF-----------TYTVYPHADsWEsa 922
gi 81834505  834 VADar----sgVSLMNDSKYGHDArRTdtGTLLRLSLLRgpewpDPKADLGEHSF-----------RYALYPHPGdWRea 898
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3CZN_A       904 rPSKLHPagyltsaahkasqSLLDPLDKfifaenewigaqgqfgGDHP-S--AREDLDVSVM--------RRLtkssakt 972
gi 81849259  909 nVVHEAH-------------EVNAPIQViys-----------enLGENlVkeAMASIDCENViidtikkaEDGd------ 958
gi 81849177  930 hTVQKAY-------------ELNQPLYTrvc----------ekhEGILeDtlGLVKVNKDNImievikkaEDTd------ 980
gi 81324155  937 gTATAAW-------------ALNNPLLAv--------------pGASAfAgkSLLRADGAHIafdaikkaEDEd------ 983
gi 81849795  932 eTVQAAW-------------ELNNPIFT----------------SNGEiEtfSLFQVTNPYVmidsvkqaEDGn------ 976
gi 81857896  930 dVEREAT-------------YLQSAIIAvp-------------gEAEMpFdqPLFTVSSDQVivdaikksEDGt------ 977
gi 74556577  856 eVIKRAY-------------ELNVPLRVv--------------kGVSEvKrkSFIRINDSKLileavkvaEDD------- 901
gi 74574247  839 eVIKRAY-------------ELNIPIKIv--------------rGKSAeKekSFVKINNLilea--vkiaEDDd------ 883
gi 81853094  923 hTVQKGY-------------ELNIPLQVilnpvpns-qlltshyPPNMrDrvSFVNLPAENLvlmaikpsEDD------- 981
gi 81834505  899 aTVRAGL-------------EFNTPLHAlp------------qtIHPGtLpeSFLQLDNPQVvvaawkqvEDGk------ 947
                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
3CZN_A       973 qrV-GYVLHRTNLMq---------CGT-PEEHTQKLDVCHLLPNVARCerttltflqnlehldgmvaPEVCPMETAAY 1039
gi 81849259  959 ----QMIIRLYECHgedakakvniNVPyEKVEM--VNLIEDSIDGKelnk-------------etmhLTFKPFEVHTL 1017
gi 81849177  981 ----HLIIRMYEFFnsrtkstlefSREiEEAFE--CNLMERNLEEAkfeg-------------ekieFTINPFEIKTF 1039
gi 81324155  984 ----ALVVRLHEYAggrglttltpGCEiASWQE--CDLLERPIGDRhdgd-------------kplrFELAPYEIKTF 1042
gi 81849795  977 ----GFILRLHEFAgthgevtfnsDYTiTSITE--CNLLEENetsl-----------------ptptFTIAPFEIKTY 1031
gi 81857896  978 ----SVIIRLHEMEgaratvkldcRYEaKQWRE--VNLIESEALSewst--------------rpveLTFTPYEIKTI 1035
gi 74556577  902 --NnSVVLRLYEYEntrgeayvevPFNvTEARS--LDLLELNEVPRDIvieg-----------nrikVKYKNRDILTI 964
gi 74574247  884 ----SLIFRLYDVEnvrdeceivlPFEvLSAES--LDLLELNRVPRVVkves-----------nkvrVSFKNRDILTL 944
gi 81853094  982 --QqQLILRFYESHgvtte--lslqsDlNLTLGTPVDLLERPTSqfsf---------------qqqiSTIEPWKIATF 1040
gi 81834505  948 ----GWLLRLYESQgqpaaarlrlAIPvRSVVK--TDLLERPIAALavqd-------------gqasLQLGPYEIQTV 1006
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