5JM0


Conserved Protein Domain Family
Glyco_hydro_38C

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pfam07748: Glyco_hydro_38C 
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Glycosyl hydrolases family 38 C-terminal domain
Glycosyl hydrolases are key enzymes of carbohydrate metabolism.
Statistics
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PSSM-Id: 336798
View PSSM: pfam07748
Aligned: 46 rows
Threshold Bit Score: 125.586
Threshold Setting Gi: 81526010
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5JM0_A       685 LVEMRTLTWSKPEKVSEEcslngsytss---------------------------------------------vtgyddy 719
gi 81849259  632 AILVNSLSWSREQWIKLYdrwtkvnlnslsgeiikke----------------------------eiepyceistlkvse 683
gi 81849177  622 VVVFNSLVFERDDIATFDvpedienpavldgeeeiicqriddwekaiffa--kgipangyksfkiiestnkevenvslne 699
gi 81324155  627 VSVYNGAAFDRTELVEIPvqagigsqggwlgeagrplraefdgsrwlvlaedvpatgaatlrfdpsagqqtsvkafewad 706
gi 81849795  623 ITLWNSSTWTRPRYIEISpenpadhlafydennillpaqklvnntwliqh-pnlpvlgaatisvketpnilgqssfnynn 701
gi 81857896  622 WTFFHPYQYDTPILVTIPkgtderfvdqtghglssqqtannetlvlleks--ipfayqtisratmvaeevqmlsqvnfee 699
gi 74556577  578 TFVFNSLSWDREEYIEADgklvkvrvpsvgfsllep-----------------------------vevrdkavinennae 628
gi 74574247  563 IYLFNSLNWDREEYVEINgkfykvkvpsigftafkp-----------------------------eevkekvnvkefedy 613
gi 81853094  610 IFVFNSLNWQRSEVVSVTlpppptnqqwqvydttgeqiisqltepstllflakdipsvgyrlfwlsptsppsptsptsld 689
gi 81834505  592 VVVFNSLATPRDAPVALPapgnlrgarlvavdrtgkdvpvqaagdwlh------fwaagvpgighkvfwlrpadapapat 665
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5JM0_A       720 ivlANGKLKVIICKKtGVITSITDETLGVEYLDtehgrnkL--GANQFVIYDDkplgwqawdTELYsvnqy-kyvtkPKK 796
gi 81849259  684 nnlENGLVKVEFNEN-GTIARIFDKELNKEVLR-------De-KGNELRVYEDngd---awdFSGVyedrpseifelVKS 751
gi 81849177  700 keaENDFLRIKFNEE-GNIVSLFDKRAEREVLK-------EgtLGNRLQAFEDkpmeysnwdIDIYykekm-wnvddVQS 770
gi 81324155  707 gvlRTPHYELAFDEA-GRLVRLYDRGLSREVLP-------RgaRANELQVFEDkpkmfeawdIDLFyqekr-revtdLRK 777
gi 81849795  702 kqlETPFYQIKWNEV-GQFTSIFDKKNNRQVLA-------EntRGNVFQLFEDkpmwhdawdIDLFyqekq-neitaLDS 772
gi 81857896  700 rrwETPWYQLEWNDE-GQFIRMYDKLGKREWLA-------QgkLGNVFKRFEDkplahdawdIDLFyqeks-stvssFQG 770
gi 74556577  629 ylvENKYFRVRISKS-GQVLSLFDKEANREVLR-------D--KSNLLIAYENipgwadawdIEKGfedrs--feirASS 696
gi 74574247  614 yqiENKFFVLKLGKE-GKLLSLYDKEAKREVLK-------G--PSNVLTFYENipgwadawdIEKGyeetn--fvvkASS 681
gi 81853094  690 yvlENEHLRVIVDPDtGDLSSIYDKTHQREILS-------G--AGNQLQAFKDsgqywdawnIDPSysqhp-lpatnLKS 759
gi 81834505  666 tglENAYLRVEVDPRtGDLASIFDKRTGRETLN-------G--PGNRLQFFKDegqywdawnIDPDyekhp-leaptLVS 735
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5JM0_A       797 VQVSCNTKEKCAvevifqisEKCKIKSVISLNATAvtdaklSKVDISTTVeNWDARNKFLKVEFPVNIRNDFASYETQFG 876
gi 81849259  752 EVIV--DGPKATikqn-ykyGDSTLVQEISILEGS------KRIDFKTKV-DWKENGKMLRTSFNTNVYTREADCEIQFG 821
gi 81849177  771 IEVVEEGPVRSTlrie-rkfLESTIVQNIYVYRDL------DRIDFNSYV-DWKEHEVLLKTSFPIDLNATEATYEIQYG 842
gi 81324155  778 LELVECGALRAVlrle-wayGASVIEQRLVVYADD------RRIDFVTRV-DWREHQQLLKVAFPVEIRATEATYDIQFG 849
gi 81849795  773 VEITEKGPLQFTmkqv-lhsEKSQITQWIHFYHES------PEIRFETEV-DWRDRNQLLKVAFPVDVHASEASYDIQFG 844
gi 81857896  771 CELIENGPLRTTvlfr-wkeDGVVIKQAIRCYRHT------ARIDFATEV-DWQARQQLLKVEFPVDIRTNEAIYDIQFG 842
gi 74556577  697 SEIVNNDGIVASikft-ykfRRSEIIQIVRVYADS------RRIDFITTL-RMRDRELLVKSWFNFDLNVERAVSDIPFG 768
gi 74574247  682 STVI--EDTVVNvkyt-ykfRNSEVYQIVRIYPDH------RRIDFITTL-RMRDRELLLKAWFNFDVNTDKAISDIPFG 751
gi 81853094  760 IQWLEQGAVQNRlrvv-rqlGESEFCQDYILQVGS------PQLKIASRV-NWREKQVLVKAAFPLNLTADFATYEIPCG 831
gi 81834505  736 LQTVEQGPVRAVvrvv-rrfRQSTFEQDLILYRDA------PHLEIANRV-DWQERHVFVKAAFPLAVRSEQATYEIPFA 807
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5JM0_A       877 ITKRPthyntsWDVAKFEVCHHKFADYSEys----kgVSILNDCKYGFST-H---GNLMRLSLLRspkapDAHADMGTHE 948
gi 81849259  822 TIKRPthgntsWDMAKGEICAQRWIDLSQrd----ygVALINDSKYGHNVs----ETKIDLNLLRspgypDPNADRGEHE 893
gi 81849177  843 NVKRPthsntsWDEARFEVCGQKWADLSEgd----fgVSLLNNCKYGHDIq----DGDMRLTLLKsgthpWTETDQEEHF 914
gi 81324155  850 NVKRPthwntsWDHARFETVGHQWVDLSErg----ygVSLLNDCKYGHDIk----DNVIRLSLIKsaidpDPNADQGEHL 921
gi 81849795  845 NVKRPthwntsWDYARFETVGHQWADLSEkn----ygVSLLNDSKYGYDIk----DSTIRLTLLKaagypDPDADLGIHQ 916
gi 81857896  843 NLKRPthwntsWDMARFETVGHKWAAIAEad----ygISLLNDSKYGYSIk----DNVLSLSLLKgaiypDPEADIGNHQ 914
gi 74556577  769 VVERFtwsntsWDKARFEVPIQKFVDFSEse----ygAALLNNGKYGATLr----GSSVGLSLTKtpiypDPSTDLEEVT 840
gi 74574247  752 VIERFtwqntsWDMARFEVPIQKFVDLSEgn----ygVALLSEGKYGVSLr----GTSVGLSLTKtplypDPTTDLEEVT 823
gi 81853094  832 AIRRPtqpqnpQDKAKWEVPALRWADLTAdtdkgiygVSLLNDCKYGYDSq----PQLLRLTLLRsptwpDPEADTGIHE 907
gi 81834505  808 TIERStlrdtpARKAQWEVPALRWADVADar----sgVSLMNDSKYGHDArRtdtGTLLRLSLLRgpewpDPKADLGEHS 883
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5JM0_A       949 IKYAIYPHRG-ALssdTVKLAHEFNYCFKYkl-----------pkDIGMNFddIISISGDENVilsnikrgEDdsavksn 1016
gi 81849259  894 FTYCLFPHRGdYIegnVVHEAHEVNAPIQViys----------enLGENLVkeAMASIDCENViidtikkaED------- 956
gi 81849177  915 FTYSIYPHMGtWKeahTVQKAYELNQPLYTrvc---------ekhEGILEDtlGLVKVNKDNImievikkaED------- 978
gi 81324155  922 FTYSLYPHAGdWAsggTATAAWALNNPLLAv-------------pGASAFAgkSLLRADGAHIafdaikkaED------- 981
gi 81849795  917 FTYSLYPHQGdFLdgeTVQAAWELNNPIFT---------------SNGEIEtfSLFQVTNPYVmidsvkqaED------- 974
gi 81857896  915 FTYALYPFQGpAFkrdVEREATYLQSAIIAvp------------gEAEMPFdqPLFTVSSDQVivdaikksED------- 975
gi 74556577  841 FIYSLYPHIGdWKraeVIKRAYELNVPLRVv-------------kGVSEVKrkSFIRINDSKLileavkvaED------- 900
gi 74574247  824 FTYSLYPHIGdWRkaeVIKRAYELNIPIKIv-------------rGKSAEKekSFVKINNLilea--vkiaED------- 881
gi 81853094  908 FTYTVYPHADsWEsahTVQKGYELNIPLQVilnpvpnsqlltshyPPNMRDrvSFVNLPAENLvlmaikpsED------- 980
gi 81834505  884 FRYALYPHPGdWReaaTVRAGLEFNTPLHAlp-----------qtIHPGTLpeSFLQLDNPQVvvaawkqvED------- 945
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5JM0_A      1017 yslnprDeQ-SIVVRVYESLGGESFASLNT--TLNLKRIEKVDNLEMKVYKSLTatrdesnhainripIKLRPFEIASFR 1093
gi 81849259  957 ------Gd--QMIIRLYECHGEDAKAKVNInvPYEKVEM--VNLIEDSIDGKelnk--------etmhLTFKPFEVHTLK 1018
gi 81849177  979 ------Td--HLIIRMYEFFNSRTKSTLEFsrEIEEAFE--CNLMERNLEEAkfeg--------ekieFTINPFEIKTFK 1040
gi 81324155  982 ------Ed--ALVVRLHEYAGGRGLTTLTPgcEIASWQE--CDLLERPIGDRhdgd--------kplrFELAPYEIKTFL 1043
gi 81849795  975 ------Gn--GFILRLHEFAGTHGEVTFNSdyTITSITE--CNLLEENetsl------------ptptFTIAPFEIKTYR 1032
gi 81857896  976 ------Gt--SVIIRLHEMEGARATVKLDCryEAKQWRE--VNLIESEALSewst---------rpveLTFTPYEIKTIE 1036
gi 74556577  901 ------D-NnSVVLRLYEYENTRGEAYVEVpfNVTEARS--LDLLELNEVPRDIvieg------nrikVKYKNRDILTIS 965
gi 74574247  882 ------Dd--SLIFRLYDVENVRDECEIVLpfEVLSAES--LDLLELNRVPRVVkves------nkvrVSFKNRDILTLR 945
gi 81853094  981 ------D-QqQLILRFYESHGVTTELSLQS--DLNLTLGTPVDLLERPTSqfsf----------qqqiSTIEPWKIATFK 1041
gi 81834505  946 ------Gk--GWLLRLYESQGQPAAARLRLaiPVRSVVK--TDLLERPIAALavqd--------gqasLQLGPYEIQTVR 1007
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