Conserved Protein Domain Family
DUF1620

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pfam07774: DUF1620 
Protein of unknown function (DUF1620)
These sequences are mainly derived from predicted eukaryotic proteins. The region in question lies towards the C-terminus of these large proteins and is approximately 300 amino acid residues long.
Statistics
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PSSM-Id: 336808
View PSSM: pfam07774
Aligned: 167 rows
Threshold Bit Score: 112.583
Threshold Setting Gi: 74777681
Created: 20-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74780791   360 SENWLVYSYYNDKARRTEMTSIELYEGKTQtnstvwss------------------ldapplpMV--ERQSYIL--PMAV 417
gi 74777681   734 FQNIILITSFHSNYKVPVILILELFQFIKDetstginmldkfiflv--sskknvkeskiysekHVhvQETTFLYnyELPI 811
gi 124461151  116 DDHKVFVTYQNQAKMIFEIWTVEIYHMKRSvhlqkcqsiiislkiqqiniimkqntilfsnskyidfLQQVYGF--PLGI 193
gi 124465929  666 DEHQVFVTYYNKAQMMFEIWTVEIYHAKIEvsfikmlenyyft-------ktpiitnyykadfEAffLQQVYGY--PLGI 736
gi 121983596  775 DENGVFVSYYNPVYSIFQIWTVELFSKKMEnnfvsmlqnyyfses----gakyedfnylnenmDIiaLEQKYGY--SLGI 848
gi 168025171  780 SENWVVYHYFNLRQHRYEMSVLEIYDQSRLpdkgviqlmlgqhn------ssvpissyspvnlEV--KQQSYFF--TFTV 849
gi 302765084  725 SENWVVYCYFNVRNHRHEMSVLEVYDKSADgkdvlqlmlgryn-------asvpfssfsprnlEV--KGQSYFF--PSTV 793
gi 290999581  698 DENTLVYQYTNAKQMRHELTTVELFNNGTDfqkkgfgsilmeklfg--skeagvftsfgyskpTS--RKNTYIL--PFGV 771
gi 552823122  736 TENMAAYHFWSSEAHRWQMATVELYDASPPtlkvsdlafget---------nltssswdvpplEA--GSQTFLC--RLPV 802
gi 159463866  281 SENLVLYHFRDVESGRFVACSMEMYDATPGrefsvldylfnpn-------stqpvssltptpiEV--VSQSYFS--RIVP 349
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74780791   418 AALKETITEKGITSKHILIGLTTGAVAE-MTWALLDPRRPVts-----peKA------RE--EGIVPympelplpHEILI 483
gi 74777681   812 DYSLLSKTSESLASKIILFGSEKSNVFEcIPERLFSTLRPN-----------------KSk-KKNLIhnsn-lpfYQSIL 872
gi 124461151  194 KYLGITRTRKSLTKKNLLIITTFSQMYQ-LDRNLVSARRREnsd----ldHPfvql----------------tyrLFNMN 252
gi 124465929  737 KYLGMSRTQKSLTKKNLLIITTSGQLHS-LDRNLVSTRRREka------dQPile-ysLQs-AELPPyqyqlpinFLNML 807
gi 121983596  849 KKMAVVTTKLSLTKRNLMIITPNNQIHS-LDRDILSTRRAVklp----kdNQlqnafsFEs-TTLPPynymvpidRLSII 922
gi 168025171  850 KTMTVTSTAKGITAKQLLLGTVNDQVLA-LDKRLFDPRRTLtp-----tpAE------QE--EGILPltdsipisPQSYL 915
gi 302765084  794 RTMSVTFTARGITGKQILVGTIGNQVIA-LDKRFLDPRRSadp-----tpME------RE--EGVIPlseglpvfPQSYL 859
gi 290999581  772 RSIGVTKTTIGVTNKQFILSLTNDQIYL-VDKKIIDARRPRnp-----taAS------DEiaEGLMPynpyipfvSLNVP 839
gi 552823122  803 VGLSVTRSLRGNTAKQVMLLTQAGQVYL-LDRRFLDPRRPIvppgqkptpEQ------AA--EQLPAyqaelplsGPMFA 873
gi 159463866  350 TGLAVTRTEQGITAKQLLVVTNTDQVYA-LDRRWVDPRRPKkqk---ltqDE------ME--EGLTPyqdtlpfsPLSFA 417
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74780791   484 NYNQTVTHIR--------GIHTAPS---------GLESTCLVLVHGLDLFVTR-VSPSKTFDLLKEDFDYFLITVVLVVL 545
gi 74777681   873 SE-----RIKfstkfnskKIFSFPHe--------TYESKSKLLSVGFNSLEVFeIYPNTSFDLLPYDFNYYNIINTVFLI 939
gi 124461151  253 SLF-IF-KVC--------QLTIKHSiskgfqqnlQIQNPMPFLSF---MVLTI-ITPYKSYDMVQKNFNYDAVILTTVLI 318
gi 124465929  808 SYHQTF-DIE--------KFSIEST---------NLESSALLLVYGSDIFFTR-IAPDKTYDMLLDNFNYNALIVTTVLI 868
gi 121983596  923 SYHANLNDIK--------EIYFSGS---------NLESTILFVAYGNDVFMSS-IAPDRTYDMINEDFNYILVTLSIIIC 984
gi 168025171  916 THSYQVEGLR--------GLLTIPA---------RLESTSLVFAYGLDLFYTH-TAPSKIYDSLTEDFSYALLLVTIVVL 977
gi 302765084  860 THAARVEELR--------GIISVPA---------RLESTCLVFAYGIDLFFTR-TAPSRTYDSLTEDFSYALLLITIVVL 921
gi 290999581  840 TYNKPVSRVK--------HIQTSPS---------ILESTTLMASSGLDVFFTR-LSPSKKFDILNEDFSYAMLIISTSAL 901
gi 552823122  874 TLNHEVKRLR--------GVAVEAA---------ELESTMLMLGHGLDLFYTR-LTPSKSFDMVPDDFPYALLVLIVVSL 935
gi 159463866  418 TLDKQVLGLR--------AVTVEPT---------RLESTCLMFAHGVDLFYTR-LAPAKGFDSLEDDFNYALLIAALVAL 479
                         250       260
                  ....*....|....*....|
gi 74780791   546 TTTSFVVKQLASKKLVKQAW 565
gi 74777681   940 LTITAISIYFSKRNQLK-KW 958
gi 124461151  319 TLTIQVSQKLIKSSKQVKQF 338
gi 124465929  869 VVATKVLSKLVKSSKQVKQF 888
gi 121983596  985 FVGVFIAKKYASQSNLH-RL 1003
gi 168025171  978 FLSIIVTYVLSERRELAEKW 997
gi 302765084  922 VVAIAVSMVLSQRKELREKW 941
gi 290999581  902 FISVFVAKYLANKKEVQLKW 921
gi 552823122  936 TTATVVLSFLQSKGTMKAKW 955
gi 159463866  480 SVGAVIMNYMTKQAQLAWKW 499
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