Conserved Protein Domain Family
COX4_pro_2

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pfam07835: COX4_pro_2 
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Bacterial aa3 type cytochrome c oxidase subunit IV
Bacterial cytochrome c oxidase is found bound to the to the cell membrane, where it is involved in the generation of the transmembrane proton electrochemical gradient. It is composed of four subunits. Subunit IV consists of one transmembrane helix that does not interact directly with the other subunits, but maintains its position by indirect contacts via phospholipid molecules found in the structure. The function of subunit IV is as yet unknown.
Statistics
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PSSM-Id: 311675
View PSSM: pfam07835
Aligned: 39 rows
Threshold Bit Score: 38.8802
Threshold Setting Gi: 568320369
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
1M56_D         9 HG---HVAGSMDITQQEKTFAGFVRMVTWAAVVIVAALIFLALAN 50
gi 123591188  16 HPahgHVAGSMDITQQEKTFAGFVRMVTWAAVVIVAALIFLALAN 60
gi 122972601   6 HG-------EMDIEAQEKTFDGFMRWSMRTVIAIIVLIIWMAIFI 43
gi 123027660   8 RG-------EMDIHAQKATWDGFMAGSTWGSLIIIMTVGYATLAI 45
gi 81534376    7 RG-------EMDIQEQAATYDAFGKMTKWGSLAISVLLLFFTLLF 44
gi 501130897   7 HG-------SMDISEQEKTFHGFLAITKWTTISIIVFLILLYMIN 44
gi 501241938   7 RG-------EMDIHEQAATFEGFGKMTKWGSLAIAVLLLTITLWF 44
gi 503244390  11 KG-------EMNIHEQSETYDLFMGLTKWGSLIIAVGILFFVLLF 48
gi 530324240  12 HG-------EMDIRVHQKTFAGFIRLATWVCGISAAVLVFMALVN 49
gi 753757248  12 HG-------EMDIRHQQATFAGFIKGATWVSILSIAVLVFLALAN 49
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