Conserved Protein Domain Family
DM4_12

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pfam07841: DM4_12 
DM4/DM12 family
This family contains sequences derived from hypothetical proteins expressed by two insect species, D. melanogaster and A. gambiae. The region in question is approximately 115 amino acid residues long and contains four highly- conserved cysteine residues.
Statistics
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PSSM-Id: 336836
View PSSM: pfam07841
Aligned: 180 rows
Threshold Bit Score: 48.8094
Threshold Setting Gi: 241753563
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121990555 351 RQLLFGKIERLYKAQQL--NGTACVLRALCESAQ---RqQQSDGgegggakafrpqSF----------IME-------L- 407
gi 121957100 132 FTQLLNKVDDMLAQNNI--DSGSCLQKAICTYVQ---KsDYHMQv-----------GT----------ADQ-------I- 177
gi 307197817  76 FTQTLTKVDDVLARHGI--DTTSCMQRVVCTYSQqaaA-SVNEEd-----------NI----------INDkissfnkI- 130
gi 321462489  87 FMELLAMLDETFRKMQI--HNFDCQKRAVCEAHQ-----PHSDKk-----------SIepfvrrityiFGK-------Ld 141
gi 242018715  99 FTDVINKIQESLNGYNV--ASSGCVQRAICQSIQ---TaNEKVEn-----------RT----------ANE-------L- 144
gi 241852623  64 mMSLLSRLDEAVQKYGS--QEAACQLRAMCELHR---G-GMSPEa-----------GV----------IAK-------N- 108
gi 968071761 236 HGMLFDVLTLLAEIHSY--QPRYCIMRTLCESRH---LlAAPGT------------SL----------FHD-------I- 280
gi 241753563  72 QVEEYFQFIR-----AH--DEDQCLARLICMMST---Epn--------------gfGA----------YAK-------Q- 109
gi 357607738 141 MLKTYVR--------SFgtNDDKCLQKYICDANS---EcSADIGp----------kSV----------FCQ-------Lg 182
gi 170067212 200 VLKTYAR--------TYnnSQDKCLLKYICEANN---DcVNAIGg----------sNI----------FCQ-------Lg 241
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 121990555 408 ---LSAIFqL--PASNDGdevealALKhISp------HYLEAHRQQGn----CPQLY-S-DC 452
gi 121957100 178 ---EHMILaL--AENSLV------DYMlDGt------AIKEAIKNGKaqsrsCDELY-K-SC 220
gi 307197817 131 ---VNTII-T----NSVF------HTAmQGt------AIQEAIETGRtg-knCLKSY-P-HC 169
gi 321462489 142 dkaLDAL---------EP------ESAdFLl------KYFEAAEKGKsn-enCSQLY-A-TC 179
gi 242018715 145 ---ENIVDvL--SKNDLM------KTFlDGt------DLKKAIEYGEkk-knCHLEF-K-NC 186
gi 241852623 109 ---LISLL-K--VESRVE------RSTmPDdqktalrDFLRAAQHGLhh-rnCTQIY-SgEC 156
gi 968071761 281 ---FRILLrYvfPEIA------------HKp------TYREAFTAGHsm-hkCASLYgP-HC 319
gi 241753563 110 ---IDSFFrAysPRSS----------QqSAa------FYKEAATASRsn-edCATRF-A-QC 149
gi 357607738 183 tyaASFVMeR--QSGG------------TFn------QFFEAGRRGRsg-idCRQLY-L-EC 221
gi 170067212 242 nyaASYIIeR--QTNK------------PFe------SLYEAGRNGRlg-qnCRQLY-L-EC 280
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