Conserved Protein Domain Family
Eaf7

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pfam07904: Eaf7 
Chromatin modification-related protein EAF7
The S. cerevisiae member of this family is part of NuA4, the only essential histone acetyltransferase complex in Saccharomyces cerevisiae involved in global histone acetylation.
Statistics
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PSSM-Id: 311728
View PSSM: pfam07904
Aligned: 61 rows
Threshold Bit Score: 76.5031
Threshold Setting Gi: 74966779
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74607617   18 EEIRLFKWM-M-LFKPAGIHKHFHMVCLLERLNKpdqyp----------------------ikllQSDkgSSDKVFSGED 73
gi 74635534   39 SETVLFNSL-C-KFKPVGIHKHFRMISLSASLNYy------------------------------FSEspKDAPVFSHQD 86
gi 74582144   37 EETLLLKAI-CrGLRPVGIEKNFYMIGILREIRDg-----------------------------------CKRSTIKAQD 80
gi 575484778  95 MEMTLFQAV-A-KYRPIGVHKHFRILNVQRFINT-------------------------------H-----MGTDISIQE 136
gi 527304537  19 GEIAFFRSM-M-RARPVGLHRHFHLLTIRNAILR------------------------------------DTGRSVSTDD 60
gi 213410208  29 EETALLRAIcM-GLRPVGVHRHFHMLNILRQLN-------------------------------------AKSQHKRVQD 70
gi 393912400  35 SEIRLFKKL-L-SHKPAGVSKHFHMGCLVDYMNNvyededtdfedvltsedlhelttkrnttgkpRVFrpRYKIRPTAGL 112
gi 511000895  41 MELALLNAI-S-RCKPVGIHKHFRIISVQRQFNQ-------------------------------N-----SPVACSIKE 82
gi 170089299  21 GEISFFRSI-M-RARPVGIHRYFHVLTIQSSIFK------------------------------------DTGRTIHIDS 62
gi 443923596  50 GEIALFRSI-E-RARPVGMHKHFHMLTLRRSIRN------------------------------------ESGFWVNVAD 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74607617   74 VWEQLSRYYNLEKADEV--ENQPYPEFYNDDGPTE--------------TTnkktegdaqldndddsdndvdncdelkrn 137
gi 74635534   87 VWDKLGTLYDLDGLDEL--EYVADNQDSDMDEDED--------------DEaaiegia---------------------- 128
gi 74582144   81 VWNKLGTLYNLKEFEEL--EAPGNEEVKAKEKriksp------------------------------------------- 115
gi 575484778 137 LWNRLSIYYNIEKLDEL--ADDTEADVPYERRIHR--------------AIfpft------------------------- 175
gi 527304537  61 VWRKIRSCYDLDILEGI--EVDGYDLPGAQDVPSPssnpvrspsptenlAMhpff------------------------- 113
gi 213410208  71 VWSKLESLYNLKGFEEI--ELSAEENSMFAPK-----------------PDatek------------------------- 106
gi 393912400 113 IWEKLENMYDMKEIEKN--EAI---------------------------PEglle------------------------- 138
gi 511000895  83 IWQRLGDFYGMAALDEL--EEEDEEQEEEEREEQE--------------KKkgdi------------------------- 121
gi 170089299  63 IWKKLRTCYDLDALDAIdlEAEGYYTPHSNN-------------------Stpisirspspse----------------- 106
gi 443923596  92 IWAKLATLYHLDALDDM--DEQQFHPVTGRLIVYP--------------SVwdadely---------------------- 133
                        170       180
                 ....*....|....*....|.
gi 74607617  138 iiplqnrlqqeteFELSWEDY 158
gi 74635534  129 ------krsqmkeFVLPFRDY 143
gi 74582144  116 ---------dvkdFKLPKDIL 127
gi 575484778 176 ---------tlrdFTLPSEDF 187
gi 527304537 114 ----------rheYTLPQDEt 124
gi 213410208 107 ----------lreFRLPYrfl 117
gi 393912400 139 ----------kseFCLPEDDF 149
gi 511000895 122 ----------kneFSLPLDDY 132
gi 170089299 107 --nlsrhpffkeeFSLPYDEs 125
gi 443923596 134 ------sypafneFALPYSQF 148
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