Conserved Protein Domain Family
N1221

?
pfam07923: N1221 
N1221-like protein
The sequences featured in this family are similar to a hypothetical protein product of ORF N1221 in the CPT1-SPC98 intergenic region of the yeast genome. This encodes an acidic polypeptide with several possible transmembrane regions.
Statistics
?
PSSM-Id: 311740
View PSSM: pfam07923
Aligned: 96 rows
Threshold Bit Score: 174.725
Threshold Setting Gi: 242780983
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74594254   127 PAYAFEYADCQPFPEELEEWFQYSefDRAMILAMKSSFERTWSLFcevqpslssstsWLDA--PEAMQKLFLTEVLDNLQ 204
gi 74608724   214 PRVEWYLEDSISLDDEISDWFTLA--DYSSFTHIHNAFIKHINNA-------------EAFltDETIAQLHIQKLLSNMN 278
gi 367010688  208 PRVEWLLNDFYSLSEDLPEWFCAS--DYALFQQTRIQFDHIVTDLer-----------fiS--DDAWASKAILKLVANIW 272
gi 156847112  243 PKIDWHLKNYYGLERELPEWFTLA--DYTHIPQTKSQFDKHNIVPgk-----------fiN--DEDYARTIIQSLLENLI 307
gi 403217511  225 PDVGWKLDDFYGLESELQDWFTST--DHTYLAQLRSHFVDKIKDPdm-----------flC--DEKYARAEISTMVANLE 289
gi 366995433  207 kKVEWSFKDFTSLNSELDDWFCAA--DYALLSPSKNQFMKKDINEeq-----------fMS--DDVYAEKITKSLLDLLP 271
gi 365988032  232 PSIDWEFKDFYCLQDELNDWYCNS--DFLKFPQSKGQFYQMVKLP-------------EKFlkDDSYARE----MIDMLF 292
gi 444318826  400 lKLDWSLKDFYGLNYELDNWFSSP--DFSLFKSMVHSFNSSIESPe----------dFID---DEKYCLKTINRLVDSLP 464
gi 367004701  235 PKIEVNYLGSYNLEEELPMWFSLS--DYTYLPQTKSQFKQKNIDKtl--------fmR-----DVDYARLQIKVLVNGLS 299
gi 410083673  266 sqLSWSLKYFRNLQDELPEWFTSS--DYTYFSEIKTEFEHMgg-------------nVEEFlnNMTYAKLQIDNLIKNLS 330
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74594254   205 -----------------DSELLvRLEALESVCYVVTGVWGItagkstpdyphdspiaaenAKSKSLQIQWIVTNARLIHE 267
gi 74608724   279 dn---------------------dESIVMCVAYISFGLFAF-------------------VEGKDDHLKYIKRNNMLLA- 317
gi 367010688  273 -----------------QCD----ASGLLALTYVSMGTYGL-------------------TRNFESHTLNIQRNNTLMCS 312
gi 156847112  308 -----------------EQPS----SNIMALSYIALGINPE-------------------SDSVTNQLNFMKRNNLFIVE 347
gi 403217511  290 -----------------NNMD----SNLMALTYTSLGCIVY-------------------ADDMIEHIFIIKRNNILLVQ 329
gi 366995433  272 -----------------QD----IGGNLLSLFYISMGIFGK-------------------AKSMNDHLTYIRRNTMFMI- 310
gi 365988032  293 -----------------HASNL-TDSALMTIFFISMGTFSL-------------------TRDMSEQLEQIRRNNLLLI- 334
gi 444318826  465 kkipiennskflhlnsySNDIL-HKTSILLLTYIAMGTFSL-------------------TEDINGQLIEIKKNVRLLI- 523
gi 367004701  300 -----------------TNLQ----TCIMALLFICLGIDKS-------------------NSTTKEQVLSIKRNIFLLLE 339
gi 410083673  331 -----------------NEQS----SSLLSLAYISMGTFAS-------------------CNNMVEQLSYIRRNNLLL-- 368
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74594254   268 C-SGLPSLYGCLLRAFEKSRVSAPSesnaasesanpmllAAADR---EANLVLTAFYLMVETARMqetr----------- 332
gi 74608724   318 --EHLPEILKKFIEIADCCKDSS----------------TNLNCyskSLLYLSSVIYLITLQCIVfrc------------ 367
gi 367010688  313 S---LPELIQAFKDIAIKCRDDH----------------NELKQkttLLFYSSTILYFIVNVCIDsr------------- 360
gi 156847112  348 I--GLDKIVKSFFKIASSCRDa----------------nSNLRKhtvLLFYSSTILFCIISICIEer------------- 396
gi 403217511  330 ---VLPQLIGVFKKISAACRDDK----------------SNLRRkttLLFYVATTLFFIISVCIElr------------- 377
gi 366995433  311 --PQLPILIKTFKEICISCRDn----------------kNNLKRqstFLFYSSSILFLIATICIEsrd------------ 360
gi 365988032  335 --PHLDTLLENFKKIAIKCRDSr----------------GNLKKhssLLFYSSSVIYFIVCVCIEnr------------- 383
gi 444318826  524 --PNLLKIIESFKFIAIQCRDSEVD----------------LKNksqQLFCMSTIIYFIVSVCLEerelyfqnekikldn 585
gi 367004701  340 DeNNLITIVKRFYDISNNCRDKt----------------SNLNLqttLFFYTMTIIFLIATVCIEerf------------ 391
gi 410083673  369 C-DNLDAIIETFKELAMACKDDE----------------TNLKRnttLFYYSSTILYFVTTVAIEkr------------- 418
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74594254   333 ------dpkHTPLRDA----ITA--L--E----PDLMVFLIEIIARLRWDDASNIPLTRIILLFWKCILLFFGGSDMLKQ 394
gi 74608724   368 ------nkeQQHIVDK----VIG--NfdD----AGILSYLTKYIEAWRWNSRLSMRIRNIIMLLSKVILLQFGDIRTYKK 431
gi 367010688  361 -------qeRPDLVQR----AIK--VieE----AKLLQFLTRYIEHWRWNSRLSMRIRNIINLLYKLLVLQFGDKKLHKR 423
gi 156847112  397 -------nnNEKIIKE----AIS--TfdK----LKLLQFLTKYIEHWRWNSRLSMRIRNIISLLFKALTLQFGDQDIYRE 459
gi 403217511  378 -------deYSGDVTN----CIThiS--D----AGLLKYLTGYIEYWRWNSRLSMRIRNINALLYKALVLQFGDNRRCKE 440
gi 366995433  361 -------gkSSEFIQT----VIH--FfdD----DAVLQFLTKYIEHWRWNSRLSMRVRNIISLLFKLITLQFGDRSLYTT 423
gi 365988032  384 -------dnAKVNITI----TAF--Y--E----ARILEFLTFYIEQWRWNSRLSMRIRNIILLLFKLLVLQFGDKNLYNE 444
gi 444318826  586 nspyygnldKTNSRDEtnfiFMA--I--EyfqsSGFLQFLTRYIEHWRWSSRLSMRIRNIINLCFKLLVLQFGDRDLYKV 661
gi 367004701  392 ------neaRKPIIDN----TIN--IfeD----MKLLLYLVKYIEHWRWNSRLSMKIRNIINLLSKVIILQFGDDAVFKK 455
gi 410083673  419 -------dtKKTEVDK----IIG--AfeR----SEILSFLVKYIEQWRWHSRLSMRIRNMISLLFKLLLLQFGDEKVYNR 481
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 74594254   395 AKETLEPa-----fDCgKND-----PTRRtPF-LT----ASPLDYHNFRQEITSKYPAYNPPP 442
gi 74608724   432 TKKDLYKyh--------glR-----KIENrKNkWT----ISPLQYEAFTSDIVTRYPSCKLPT 477
gi 367010688  424 TKKRICQm-----hDI-KDT-----NNGNtKK-CT----ISPLYYQAFREDITARFPNYITPK 470
gi 156847112  460 TKYTIEKv-----hGIkRSE-----GCQNm-K-LD----ISPLHYQAFREDIVSRYPDFDPPS 506
gi 403217511  441 VKRKLYKy-----hGIsHSD-----DKSNr---LT----LSPLQFEAFSEDITSRFPAYDMPA 486
gi 366995433  424 TKKQLYNf-----hGLnAYN-----NDEEgKR-LT----VSPLHYKAFQEDITSRFPEYPMPT 471
gi 365988032  445 TKSSLYEl-----hGLePHKrkyggYAKGsTK-LS----ISPLHYRAFRDDITSRFPDYSMET 497
gi 444318826  662 AKSEISKl-----hGI--DI-----EKKTsKN-LT----ISPLHYQAFREDIISRYPDCKLPL 707
gi 367004701  456 TKREIYKlhkvtfyEDeEEN-----ITESaNC-IKsklgISPLSYEAFREDIISRYPDLVIPN 512
gi 410083673  482 TKASVYSh-----nNLiYSK-----DSRFnAN-LS----VSPLQYLAFREDIRSRFPEYELPE 529
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap